ALG9
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Official Full Name
asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog -
Overview
This gene encodes an alpha-1,2-mannosyltransferase enzyme that functions in lipid-linked oligosaccharide assembly. Mutations in this gene result in congenital disorder of glycosylation type Il. Multiple transcript variants encoding different isoforms have been found for this gene. -
Synonyms
ALG9;asparagine-linked glycosylation 9, alpha-1,2-mannosyltransferase homolog (S. cerevisiae);asparagine linked glycosylation 9 homolog (yeast, alpha 1,2 mannosyltransferase) , asparagine linked glycosylation 9, alpha 1,2 mannosyltransferase homolog (
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALG9-3812H | Recombinant Human ALG9 protein, His-tagged | E.coli | Human | His | 440-618 aa | |
| ALG9-10898Z | Recombinant Zebrafish ALG9 | Mammalian Cell | Zebrafish | His |
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| ALG9-1551M | Recombinant Mouse ALG9 Protein | Mammalian Cell | Mouse | His |
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| ALG9-468H | Recombinant Human ALG9 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ALG9-8904HCL | Recombinant Human ALG9 293 Cell Lysate | HEK293 | Human | Non |
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| ALG9-1440HF | Recombinant Full Length Human ALG9 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 618 amino acids |
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| ALG9-471M | Recombinant Mouse ALG9 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ALG9-471M-B | Recombinant Mouse ALG9 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ALG9 involved in several pathways and played different roles in them. We selected most pathways ALG9 participated on our site, such as N-Glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ALG9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| N-Glycan biosynthesis | MGAT4C,FUT8A,ZNF408,ALG14,B4GALT2,B4GALT1,DPM3,GANAB,MOGS,DOLPP1 |
| Metabolic pathways | GNPDA2,PTGES3B,SDSL,ABO,PLA2G3,GPI1,FAHD1,ATP5D,NDUFA4,GALCA |
Protein Function
ALG9 has several biochemical functions, for example, dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity,dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity,mannosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ALG9 itself. We selected most functions ALG9 had, and list some proteins which have the same functions with ALG9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity | ZNF408 |
| dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity | ZNF408 |
| mannosyltransferase activity | DPY19L4,GTDC2,DPY19L1,4931440L10Rik,B3GNT8,B3GNTL1,ALG1,GALNTL4,ALG12,PIGV |
Interacting Protein
ALG9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ALG9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ALG9.
flhA;BHMT
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References
- Coss, KP; Treacy, EP; et al. Systemic gene dysregulation in classical Galactosaemia: Is there a central mechanism?. MOLECULAR GENETICS AND METABOLISM 113:177-187(2014).
- Barone, R; Fiumara, A; et al. Congenital Disorders of Glycosylation with Emphasis on Cerebellar Involvement. SEMINARS IN NEUROLOGY 34:357-366(2014).
