AKAP10
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Official Full Name
A kinase (PRKA) anchor protein 10 -
Overview
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein interacts with both the type I and type II regulatory subunits of PKA; therefore, it is a dual-specific AKAP. This protein is highly enriched in mitochondria. It contains RGS (regulator of G protein signalling) domains, in addition to a PKA-RII subunit-binding domain. The mitochondrial localization and the presence of RGS domains may have important implications for the function of this protein in PKA and G protein signal transduction. -
Synonyms
AKAP10;A kinase (PRKA) anchor protein 10;A-kinase anchor protein 10, mitochondrial;D AKAP2;dual specificity A kinase anchoring protein 2;MGC9414;mitochondrial A kinase PPKA anchor protein 10;PRKA10;protein kinase A anchoring protein 10;AKAP-10;D
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- E.Coli or Yeast
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| AKAP10-1470M | Recombinant Mouse AKAP10 Protein | Mammalian Cell | Mouse | His |
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| Akap10-3021M | Recombinant Mouse Akap10, His-tagged | E.Coli or Yeast | Mouse | His | 662 |
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| AKAP10-3022H | Recombinant Human AKAP10, His-tagged | E.Coli or Yeast | Human | His | 662 |
|
| AKAP10-396H | Recombinant Human AKAP10 Protein, GST-tagged | Wheat Germ | Human | GST |
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| AKAP10-44HCL | Recombinant Human AKAP10 cell lysate | Human | Non |
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| AKAP10-1342HF | Recombinant Full Length Human AKAP10 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 662 amino acids |
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| AKAP10-426M | Recombinant Mouse AKAP10 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| AKAP10-426M-B | Recombinant Mouse AKAP10 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
AKAP10 involved in several pathways and played different roles in them. We selected most pathways AKAP10 participated on our site, such as Factors involved in megakaryocyte development and platelet production,G Protein Signaling Pathways,Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with AKAP10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| G Protein Signaling Pathways | KCNJ3,Akap2,AKAP1,AKAP6,GNG13B,AKAP5,GNB3B,AKAP7,GNA13,AKAP4 |
| Factors involved in megakaryocyte development and platelet production | KIF22,ITPK1,H3F3B.1,ZFPM1,KIF4A,MAFG,ZFPM2A,D-AKAP2,KIF3C,MGC173646 |
| Hemostasis | AASS,ESAMA,KCNMA1,RHOGA,GAS6,RAPGEF4,RAPGEF3,GATA2A,KIF15,GATA6 |
Protein Function
AKAP10 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by AKAP10 itself. We selected most functions AKAP10 had, and list some proteins which have the same functions with AKAP10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
AKAP10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AKAP10 here. Most of them are supplied by our site. Hope this information will be useful for your research of AKAP10.
PRKAR1A
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References
- Hong, GE; Kim, JA; et al. Flavonoids Identified from Korean Scutellaria baicalensis Georgi Inhibit Inflammatory Signaling by Suppressing Activation of NF-kappa B and MAPK in RAW 264.7 Cells. EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE :-(2013).
