AGXT2
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Official Full Name
alanine--glyoxylate aminotransferase 2 -
Overview
The protein encoded by this gene is a class III pyridoxal-phosphate-dependent mitochondrial aminotransferase. It catalyzes the conversion of glyoxylate to glycine using L-alanine as the amino donor. -
Synonyms
AGXT2;alanine--glyoxylate aminotransferase 2;alanine glyoxylate aminotransferase 2;alanine--glyoxylate aminotransferase 2, mitochondrial;AGT2;beta ALAAT II;beta alanine pyruvate aminotransferase;beta-ALAAT II;beta-alanine-pyruvate aminotransferase
Recombinant Proteins
- Mouse
- Rat
- Human
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- T7
- GST
- DDK
- Myc
- Avi
- Fc
Involved Pathway
AGXT2 involved in several pathways and played different roles in them. We selected most pathways AGXT2 participated on our site, such as Alanine, aspartate and glutamate metabolism,Glycine, serine and threonine metabolism,Cysteine and methionine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with AGXT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycine, serine and threonine metabolism | GATM,PGAM1,ALAS1,SHMT2,THA1,PGAM1B,SHMT1,DLDH,AOC3,ALDH7A1 |
| Metabolic pathways | GGT7,NANSA,AK5,ACAT2,NDUFB3,PLD4,OXSM,ACOT5,CYP2J6,NDUFS8 |
| Alanine, aspartate and glutamate metabolism | ASNS,ALDH5A1,GAD1B,GPT2,GLULC,AGXT,RIMKLA,NIT2,ADSS,GLUD2 |
| Cysteine and methionine metabolism | ENOPH1,CTH,IL4I1,APIP,LDHAL6A,LDHBB,MTAP,MRI1,LDHC,GOT2B |
Protein Function
AGXT2 has several biochemical functions, for example, alanine-glyoxylate transaminase activity,catalytic activity,identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by AGXT2 itself. We selected most functions AGXT2 had, and list some proteins which have the same functions with AGXT2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alanine-glyoxylate transaminase activity | AGXT,AGXTA,AGXTB |
| pyridoxal phosphate binding | SDS,KYNU,CSAD,SHMT2,GOT1,AGXT2L2,SPTLC1,GPT2,CTHL,AGXT2L1 |
| transaminase activity | GPT2L,PHYKPL,AGXT2L1,AMT,GOT1L1,CCBL1,AGXTA,AGXTB,GOT2A,AGXT2L2 |
| catalytic activity | ACSL3A,PHKB,ACSL1B,SLC3A1,LANCL1,PFKMA,ISOC2,PKMB,MTHFD1B,ACAA1A |
| identical protein binding | UBQLN4,MCM6,BTK,HOOK2,TRP53,FBP1,GSTM3,CLDN14,E2F7,HCFC1 |
Interacting Protein
AGXT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AGXT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of AGXT2.
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