ADSSL1
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Official Full Name
adenylosuccinate synthase like 1 -
Overview
ADSSL1 is a muscle isozyme of adenylosuccinate synthase (EC 6.3.4.4), which catalyzes the initial reaction in the;conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) (Sun et al., 2005 (PubMed;15786719)). -
Synonyms
ADSSL1;adenylosuccinate synthase like 1;adenylosuccinate synthetase isozyme 1;FLJ38602;basic isozyme;muscle isozyme;Adenylosuccinate synthetase;AdSS 1;ADSS1;AMPSase 1;IMP aspartate ligase 1;IMP--aspartate ligase 1;M-type adenylosuccinate synthetase;PURA1_HUMAN;OTTHUMP00000244483;OTTHUMP00000244484;adenylosuccinate synthetase, basic isozyme;adenylosuccinate synthetase, muscle isozyme
Recombinant Proteins
- Zebrafish
- Mouse
- Bovine
- Human
- Mammalian Cells
- E.Coli/Yeast
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- Avi
- Fc
- DDK
- Myc
Involved Pathway
ADSSL1 involved in several pathways and played different roles in them. We selected most pathways ADSSL1 participated on our site, such as Alanine, aspartate and glutamate metabolism,Metabolic pathways,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADSSL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine ribonucleoside monophosphate biosynthesis | ADSL,PAICS,ADSS |
| purine nucleotides de novo biosynthesis | ATP5S,AK8,AK7 |
| Metabolic pathways | PPAP2D,NME2,COX6B1,AGPHD1,GBGT1,GGT1A,GLS2,GAPDH,FAHD1,ASS1 |
| Metabolism | HS3ST4,DPEP1,CYP51A1,CYP2R1,BRP44,CDIPT,NAT2,LRPPRC,ABHD3,C20orf7 |
| adenosine ribonucleotides de novo biosynthesis | ATP5S,AK8,ATP5L,AK7,ADSS |
| Metabolism of nucleotides | GLRX,ADK,TM9SF1,NUDT1,ADAL,ADSL,AK8,NUDT18,PAICS,TYMP |
| Purine metabolism | POLR2K,IMPDH1A,PDE7A,ENTPD6,AK3,ADKB,CECR1A,POLR3K,PDE6D,POLE3 |
| Alanine, aspartate and glutamate metabolism | ASNS,CAD,GFPT2,ADSL,GPT2,GOT2A,AGXT2,GOT1,CPS1,GFPT1 |
Protein Function
ADSSL1 has several biochemical functions, for example, GTP binding,GTPase activity,actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADSSL1 itself. We selected most functions ADSSL1 had, and list some proteins which have the same functions with ADSSL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | PVRL2,MYH9,AXIN1,GM5506,IRAK2,PVRL4,ASCL1,MAOB,ENPP1,FIGF |
| GTP binding | EHD1,MX2,RAP1B,GNAV1,DNAJC27,GNAO1A,ARL3L1,GSPT1L,SRPR,DNM2 |
| actin filament binding | CORO1A,ARPC1A,SHROOM3,TRIOBP,TNNC1,SYNE3,FSCN2,PLS1,FLNA,ACTN4 |
| GTPase activity | GBP2,RAB5C,RAB43,RAB33A,RAC3,RAB11BA,GNAI2B,RASEF,RAB3B,RAC1 |
| adenylosuccinate synthase activity | ADSS,ADSSL |
| magnesium ion binding | PI4K2A,ATP9A,EYA2,NUDT5,PTENA,GTPBP10,CLYBL,MAPK12,TSSK2,CERK |
| phosphate ion binding | GNG12,ADSS,CHST14,OTC,RELA,G6PC,RPH3A,SLC34A2,SH2B3,MTHFD2 |
Interacting Protein
ADSSL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADSSL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADSSL1.
YWHAZ;AZIN1;LYAR
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