ADAP2
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Official Full Name
ArfGAP with dual PH domains 2 -
Overview
GTPase-activating protein for the ADP ribosylation factor family (Potential). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). Possesses a stoichiometry of two binding sites for InsP4 with identical affinity. -
Synonyms
ADAP2;ArfGAP with dual PH domains 2;CENTA2;cent-b;HSA272195;arf-GAP with dual PH domain-containing protein 2;cnt-a2;centaurin beta;centaurin-alpha-2;centaurin, alpha 2;centaurin-alpha 2 protein
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ADAP2-243H | Recombinant Human ADAP2 Protein, His-tagged | E.coli | Human | His | Cys49~Ser361 | |
| Adap2-244M | Recombinant Mouse Adap2 Protein, His-tagged | E.coli | Mouse | His | Ser49~Ser361 | |
| Adap2-245R | Recombinant Rat Adap2 Protein, His-tagged | E.coli | Rat | His | Ser49~Ser360 | |
| ADAP2-0006H | Recombinant Human ADAP2 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ADAP2-509R | Recombinant Rat ADAP2 Protein | Mammalian Cell | Rat | His |
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| ADAP2-336HCL | Recombinant Human ADAP2 cell lysate | Human | Non |
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| ADAP2-165R | Recombinant Rat ADAP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ADAP2-165R-B | Recombinant Rat ADAP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ADAP2-2578HF | Recombinant Full Length Human ADAP2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 380 amino acids |
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Involved Pathway
ADAP2 involved in several pathways and played different roles in them. We selected most pathways ADAP2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ADAP2 has several biochemical functions, for example, GTPase activator activity,inositol 1,3,4,5 tetrakisphosphate binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAP2 itself. We selected most functions ADAP2 had, and list some proteins which have the same functions with ADAP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| inositol 1,3,4,5 tetrakisphosphate binding | ADAP1,AKR1C1,ITPR3,SYT2 |
| GTPase activator activity | ELMOD2,RASA3,ARHGEF12,RGS14A,RASA1,CHML,DAB2IPB,SIPA1L1,DEPDC1B,ARAP3 |
| phosphatidylinositol-3,4,5-trisphosphate binding | RACGAP1,ZFYVE1,ZFYVE16,COMMD1,PARD3,MAPKAP1,ARAP2,ARHGAP9,RS1,ANXA8 |
| protein binding | EIF1AX,ETS1,CCER1,NUP205,RARRES3,WDR6,TMEM19,SIK3,HNRPDL,PPP1R3C |
| protein binding, bridging | SH2D1B,GATAD2A,NEFH,FLRT3,FSCN2,DDX20,FGG,FBXW7,TRIM17,FSCN2A |
| phosphatidylinositol-3,4-bisphosphate binding | GAB2,D6WSU116E,RS1,COMMD1,ZFYVE1,KIF16B,TTPA,PHLDA3,PLEK,MYO1G |
| phosphatidylinositol-4,5-bisphosphate binding | FAM21C,SLC9A1,PFN2,PHLDA3,Apba1,KRIT1,SCIN,FRMPD4,ANXA2,FAM123A |
| metal ion binding | TNFSF10,AGAP5,ZNF326,TRIM55A,ZNF488,ZNF524,ZBTB16A,RNF34A,PDE1A,OASL2 |
Interacting Protein
ADAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAP2.
PRNP;IKBKG;EEF1G
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