ADAMTSL4
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Official Full Name
ADAMTS-like 4 -
Overview
This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. -
Synonyms
ADAMTSL4;ADAMTS-like 4;thrombospondin repeat containing 1 , TSRC1;ADAMTS-like protein 4;DKFZP434K1772;ADAMTS like 4;ADAMTS like protein 4;ADAMTSL 4;MGC116260;MGC28749;OTTHUMP00000032789;OTTHUMP00000032790;Thrombospondin repeat containing 1;thrombospondin repeat protein 1;TSRC1;ADAMTSL-4;thrombospondin repeat-containing protein 1
Recombinant Proteins
- Mouse
- Human
- Rat
- Mammalian Cell
- Wheat Germ
- HEK293
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ADAMTSL4-1327M | Recombinant Mouse ADAMTSL4 Protein | Mammalian Cell | Mouse | His |
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| ADAMTSL4-32H | Recombinant Human ADAMTSL4 protein, GST-tagged | Wheat Germ | Human | GST | 1-424 a.a. |
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| ADAMTSL4-33H | Recombinant Human ADAMTSL4 protein, GST-tagged | Wheat Germ | Human | GST | 1-424 a.a. |
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| ADAMTSL4-508R | Recombinant Rat ADAMTSL4 Protein | Mammalian Cell | Rat | His |
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| ADAMTSL4-27HCL | Recombinant Human ADAMTSL4 cell lysate | Human | Non |
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| ADAMTSL4-164R | Recombinant Rat ADAMTSL4 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ADAMTSL4-164R-B | Recombinant Rat ADAMTSL4 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ADAMTSL4-328M | Recombinant Mouse ADAMTSL4 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ADAMTSL4-328M-B | Recombinant Mouse ADAMTSL4 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ADAMTSL4 involved in several pathways and played different roles in them. We selected most pathways ADAMTSL4 participated on our site, such as Metabolism of proteins,O-glycosylation of TSR domain-containing proteins,O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTSL4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-translational protein modification | ADAMTS1,PROZ,KCNA6,MUC4,ADAMTS13,MUC5AC,MUC20,TRAPPC2,SLC35A1,MPDU1A |
| Metabolism of proteins | C19orf10,ST6GALNAC1.2,ALG10B,CKAP4,MUC13,MAGT1,PROCA,MTX1,CHCHD4,IGFBP2B |
| O-linked glycosylation | MUC12,B3GALTL,GCNT3,ADAMTSL3,B3GNT8,SPON1B,SPON2,ADAMTS8,ST6GALNAC2,MUC15 |
| O-glycosylation of TSR domain-containing proteins | SPON1A,SSPO,ADAMTS18,ADAMTS4,B3GALTL,ADAMTS5,ADAMTSL5,C8orf84,SPON2,SPON1B |
Protein Function
ADAMTSL4 has several biochemical functions, for example, metalloendopeptidase activity,protease binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTSL4 itself. We selected most functions ADAMTSL4 had, and list some proteins which have the same functions with ADAMTSL4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | ADAMTS12,ZMPSTE24,MMP14B,Adam6,ADAM28,MMP16,HE2,MIPEP,ADAM22,UQCRC2 |
| protease binding | CFLAR,SERPINA1,POLG,TNF,MBP,SEMG2,TIMP1,SERPINA1A,MBL1,TIMP2A |
| protein binding | CNPY2,PKMYT1,RAB6A,SELL,CRIPAK,PSMB1,SRPX2,TRIM40,GLI2,SPANXA1 |
Interacting Protein
ADAMTSL4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTSL4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTSL4.
STK16;Hoxa1;CTSB;COL8A1;AQP1;TUBGCP4;SALL2;PLSCR1;SPRY2;SORBS3
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