ADAMTSL2

  • Official Full Name

    ADAMTS-like 2
  • Overview

    This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia.
  • Synonyms

    ADAMTSL2;ADAMTS-like 2;ADAMTS-like protein 2;KIAA0605;ADAMTS like 2;ADAMTS like protein 2;ADAMTSL 2;ADAMTSL-2;ATL2_HUMAN;FLJ45164;GPHYSD1
Cat.# Product name Source (Host) Species Tag Protein Length Price
ADAMTSL2-563H Recombinant Human ADAMTSL2 protein, His&Myc-tagged E.coli Human His&Myc 861-943a.a.

    Involved Pathway

    ADAMTSL2 involved in several pathways and played different roles in them. We selected most pathways ADAMTSL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    ADAMTSL2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTSL2 itself. We selected most functions ADAMTSL2 had, and list some proteins which have the same functions with ADAMTSL2. You can find most of the proteins on our site.

    Function Related Protein

    Interacting Protein

    ADAMTSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTSL2.

    Resources

    References

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