ADAMTSL1
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Official Full Name
ADAMTS-like 1 -
Overview
This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. -
Synonyms
ADAMTSL1;ADAMTS-like 1;C9orf94, chromosome 9 open reading frame 94;ADAMTS-like protein 1;ADAMTSR1;FLJ35283;punctin;ADAM TS related protein 1;ADAM-TS related protein 1;ADAMTS like 1;ADAMTSR 1;C9orf94;Chromosome 9 open reading frame 94;MGC40193;Punctin 1;Thrombospondin;punctin-1;OTTHUMP00000021085;OTTHUMP00000021086;OTTHUMP00000021088;OTTHUMP00000239538;ADAMTSL-1
Recombinant Proteins
- Human
- Mouse
- E.coli
- Wheat Germ
- Insect Cells
- HEK293
- Mammalian Cells
- In Vitro Cell Free System
- His
- GST
- Non
- DDK&Myc
Involved Pathway
ADAMTSL1 involved in several pathways and played different roles in them. We selected most pathways ADAMTSL1 participated on our site, such as Metabolism of proteins,O-glycosylation of TSR domain-containing proteins,O-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAMTSL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Post-translational protein modification | RNF2,THSD1,B3GNT8,ADAMTSL5,ADAMTS10,ALG14,SMC5,ALG10B,PHC1,PIGK |
| O-glycosylation of TSR domain-containing proteins | ADAMTS1,ADAMTS5,THSD1,ADAMTSL5,ADAMTS10,ADAMTS3,ADAMTS15,ADAMTS18,B3GALTL,ADAMTS20 |
| O-linked glycosylation | B3GNT8,SPON1,KCNA6,SSPO,MUC1,MUC12,THSD7A,A4GNT,GALNT13,ADAMTS3 |
| Metabolism of proteins | TMED2,SERPINA7,PROZ,SLC38A8,SEC63,FURINB,RING1,UBA2,ASNA1,ARSF |
Protein Function
ADAMTSL1 has several biochemical functions, for example, metallopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAMTSL1 itself. We selected most functions ADAMTSL1 had, and list some proteins which have the same functions with ADAMTSL1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | VAT1,ZCCHC12,MMP25,ZCCHC6,SIRT3,TAF3,TRAF4,TRIM46B,ASTL,NR1I2 |
| metallopeptidase activity | ADAM8,MMP23B,ADAM17A,PSMD14,ADAM10A,DPP3,PAPPAA,ADAMTS9,ADAM28,CLCA3 |
Interacting Protein
ADAMTSL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAMTSL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAMTSL1.
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