ADAM7
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Official Full Name
ADAM metallopeptidase domain 7 -
Overview
This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein lacks protease activity and may play roles in protein-protein interactions and cell adhesion processes including sperm-egg fusion. Mutations in this gene may be involved in the progression of melanoma. -
Synonyms
ADAM7;ADAM metallopeptidase domain 7;a disintegrin and metalloproteinase domain 7;disintegrin and metalloproteinase domain-containing protein 7;EAPI;GP 83;Sperm maturation related glycoprotein GP83;epididymal apical protein I;sperm maturation-related glycoprotein GP-83;GP83;GP-83;ADAM 7;ADAM-7
Recombinant Proteins
- Human
- Mouse
- Rat
- Mus musculus
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli expression system
- His
- GST
- Non
- His&Fc&Avi
Involved Pathway
ADAM7 involved in several pathways and played different roles in them. We selected most pathways ADAM7 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ADAM7 has several biochemical functions, for example, metalloendopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM7 itself. We selected most functions ADAM7 had, and list some proteins which have the same functions with ADAM7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metalloendopeptidase activity | MMP17,MMP1,PHEX,MMP19,ADAMTS16,ADAM19,ADAM30,ADAM21,ADAMTSL5,ADAMDEC1 |
| zinc ion binding | CA9,ESRRGB,ZFP598,CPA1,TRAF7,RNF214,RNF4,MARCH1,APOBEC3B,ZNRD1 |
Interacting Protein
ADAM7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM7 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM7.
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References
- Bridges, LC; Sheppard, D; et al. ADAM disintegrin-like domain recognition by the lymphocyte integrins alpha 4 beta 1 and alpha 4 beta 7. BIOCHEMICAL JOURNAL 387:101-108(2005).
