ADAM21
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Official Full Name
a disintegrin and metallopeptidase domain 21 -
Overview
May be involved in sperm maturation and/or fertilization. May also be involved in epithelia functions associated with establishing and maintaining gradients of ions or nutrients. -
Synonyms
ADAM21;a disintegrin and metallopeptidase domain 21;Adam31;disintegrin and metalloproteinase domain-containing protein 21;ADAM 21;ADAM 31;a disintegrin and metalloprotease domain 21;a disintegrin and metalloprotease domain (ADAM) 21;disintegrin and metalloproteinase domain-containing protein 31
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- His
- GST
- Non
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ADAM21-1285M | Recombinant Mouse ADAM21 Protein | Mammalian Cells | Mouse | His |
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| ADAM21-233R | Recombinant Rhesus monkey ADAM21 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| ADAM21-282H | Recombinant Human ADAM21 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ADAM21-23HCL | Recombinant Human ADAM21 cell lysate | Human | Non |
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| ADAM21-313M | Recombinant Mouse ADAM21 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| ADAM21-313M-B | Recombinant Mouse ADAM21 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ADAM21-61R | Recombinant Rhesus Macaque ADAM21 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | Avi&Fc&His |
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| ADAM21-61R-B | Recombinant Rhesus Macaque ADAM21 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ADAM21-873HF | Recombinant Full Length Human ADAM21 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 772 amino acids |
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| TRAF6-8675H | Recombinant Human TRAF6 protein, His-tagged | E.coli | Human | His | 221-522 aa |
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Involved Pathway
ADAM21 involved in several pathways and played different roles in them. We selected most pathways ADAM21 participated on our site, such as Fertilization,Interaction With The Zona Pellucida,Reproduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADAM21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Reproduction | IZUMO4,TMEM146,CATSPER3,CATSPERB,ADAM2,IZUMO1,CATSPERG2,CATSPERG1,CATSPER1,OVGP1 |
| Interaction With The Zona Pellucida | ZP2,ADAM30,ADAM2,ADAM20,OVGP1,ZP3 |
| Fertilization | ZP3,TMEM146,ZP2,CATSPERG2,CATSPER3,CATSPER2,CATSPERB,OVGP1,ADAM30,ADAM2 |
Protein Function
ADAM21 has several biochemical functions, for example, metalloendopeptidase activity,metallopeptidase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADAM21 itself. We selected most functions ADAM21 had, and list some proteins which have the same functions with ADAM21. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | XRN2,MYLIP,ZNF259,XIRP2,LHX1B,S100A6,BARD1,ESR2A,MLLT10,LHX5 |
| metalloendopeptidase activity | MMP14,ADAM1B,MME,ADAMTS16,YBEY,MMP11,ADAM5P,C6AST1,ADAMTSL4,MBTPS2 |
| metallopeptidase activity | TMEM27,ANPEPA,C6AST4,MMP1A,ADAMTS9,ADAM10B,COPS5,BRCC3,ENPEP,ADAM2 |
Interacting Protein
ADAM21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADAM21 here. Most of them are supplied by our site. Hope this information will be useful for your research of ADAM21.
Resources
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References
- Yang, P; Baker, KA; et al. A disintegrin and metalloprotease 21 (ADAM21) is associated with neurogenesis and axonal growth in developing and adult rodent CNS. JOURNAL OF COMPARATIVE NEUROLOGY 490:163-179(2005).
