ACSBG2
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Official Full Name
acyl-CoA synthetase bubblegum family member 2 -
Overview
Long-chain-fatty-acid—CoA ligase ACSBG2 is an enzyme that in humans is encoded by the ACSBG2 gene. -
Synonyms
ACSBG2;acyl-CoA synthetase bubblegum family member 2;long-chain-fatty-acid--CoA ligase ACSBG2;BGR;bubblegum related protein;DKFZp434K1635;PRTD NY3;ACSBG 2;Acyl CoA synthetase bubblegum family member 2;BGR like;BRGL;Bubblegum related acyl CoA synthetase 2;Long chain fatty acid CoA ligase;Long chain fatty acid CoA ligase ACSBG2;MGC111089;PRTDNY3;bubblegum-related protein;PRTD-NY3
Recombinant Proteins
- Human
- Chicken
- Rat
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- In Vitro Cell Free System
- E. coli
- His
- GST
- Non
- His&Fc&Avi
- N-GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACSBG2-9316H | Recombinant Human ACSBG2, His-tagged | E.coli | Human | His | C-term-300a.a. | |
| ACSBG2-192H | Recombinant Human ACSBG2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| ACSBG2-2069C | Recombinant Chicken ACSBG2 | Mammalian Cell | Chicken | His |
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| ACSBG2-467R | Recombinant Rat ACSBG2 Protein | Mammalian Cell | Rat | His |
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| ACSBG2-6707Z | Recombinant Zebrafish ACSBG2 | Mammalian Cell | Zebrafish | His |
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| ACSBG2-18HCL | Recombinant Human ACSBG2 cell lysate | Human | Non |
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| ACSBG2-123R | Recombinant Rat ACSBG2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ACSBG2-123R-B | Recombinant Rat ACSBG2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| ACSBG2-827HF | Recombinant Full Length Human ACSBG2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 666 amino acids |
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| YWHAG-149H | Recombinant Human YWHAG protein, GST-tagged | E. coli | Human | N-GST | 1-247 aa |
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Involved Pathway
ACSBG2 involved in several pathways and played different roles in them. We selected most pathways ACSBG2 participated on our site, such as Fatty acid biosynthesis,Fatty acid degradation,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACSBG2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| PPAR signaling pathway | ACSL3,FABP4,MMP1A,PLTP,PDPK1B,ACSL4B,ACADM,FABP7,CYP8B1,PPARD |
| Metabolic pathways | POLR3GL,GAD1,NDUFA4L2,NDUFS7,DNMT3AA,ST6GALNAC4,CYP2C8,CDS2,B3GALT1,G6PC2 |
| Fatty acid metabolism | ELOVL6,ACAA1A,FADS1,ACSL4,HSD17B12A,PPT2,ELOVL5,ACSL4B,SCD,TECR |
| Fatty acid degradation | EHHADH,ALDH2,ALDH2.2,ACADL,ALDH1B1,ACAT2,ACAA1,ECI2,HADH,ADH1 |
| Fatty Acid Biosynthesis | ACSL1,ECHDC2,OLAH,ACSL5,FASN,ACSBG1,ACSL4B,OXSM,ACACB,ECHDC3 |
| Adipocytokine signaling pathway | AKT2L,LEP,AKT3A,LEPR,ADIPOQB,POMCA,RXRGB,AKT1,ACSL1A,PRKAA2 |
Protein Function
ACSBG2 has several biochemical functions, for example, ATP binding,acyl-CoA hydrolase activity,long-chain fatty acid-CoA ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACSBG2 itself. We selected most functions ACSBG2 had, and list some proteins which have the same functions with ACSBG2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | WNK1,BMPR1BB,GRK7B,P2RX6,EIF2AK2,FDXACB1,EPHB6,PKMYT1,RPS6KA6,RUVBL2 |
| acyl-CoA hydrolase activity | ACOT2,ACOT5,ACOT8,ACOT11,ACOT10,ACOT1 |
| long-chain fatty acid-CoA ligase activity | SLC27A5,SLC27A4,ACSL1,ACSBG1,SLC27A2,ACSL5,SLC27A3,SLC27A1A,ACSL3,SLC27A1B |
Interacting Protein
ACSBG2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACSBG2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACSBG2.
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References
- Pei, ZT; Jia, ZZ; et al. The second member of the human and murine "bubblegum" family is a testis- and brainstem-specific acyl-CoA synthetase. JOURNAL OF BIOLOGICAL CHEMISTRY 281:6632-6641(2006).
- Steinberg, SJ; Morgenthaler, J; et al. Very long-chain acyl-CoA synthetases - Human "bubblegum" represents a new family of proteins capable of activating very long-chain fatty acids. JOURNAL OF BIOLOGICAL CHEMISTRY 275:35162-35169(2000).
