Acot2
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Official Full Name
acyl-CoA thioesterase 2 -
Synonyms
ACOT2;MTE1;PTE2;CTE1A;PTE2A;CTE-IA;ZAP128;acyl-coenzyme A thioesterase 2, mitochondrial;long-chain acyl-CoA thioesterase 2;mitochondrial acyl-CoA thioesterase 1;acyl-coenzyme A thioester hydrolase 2a;peroxisomal long-chain acyl-coA thioesterase 2
Recombinant Proteins
- Human
- Cynomolgus
- Rat
- E.coli
- Wheat Germ
- Mammalian Cell
- E.Coli or Yeast
- HEK293
- In Vitro Cell Free System
- His
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACOT2-3247H | Recombinant Human ACOT2 protein, His-tagged | E.coli | Human | His | 222-483 aa | |
| ACOT2-12H | Recombinant Human ACOT2 protein, GST-tagged | Wheat Germ | Human | GST | 1-483 a.a. |
|
| ACOT2-266C | Recombinant Cynomolgus ACOT2 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| ACOT2-267C | Recombinant Cynomolgus ACOT2 Protein, His-tagged | Mammalian Cell | Cynomolgus | His |
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| Acot2-3138R | Recombinant Rat Acot2, His-tagged | E.Coli or Yeast | Rat | His | 453 |
|
| ACOT2-3139H | Recombinant Human ACOT2, His-tagged | E.Coli or Yeast | Human | His | 483 |
|
| ACOT2-16C | Recombinant Cynomolgus Monkey ACOT2 Protein, His (Fc)-Avi-tagged | HEK293 | Cynomolgus | His&Fc&Avi |
|
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| ACOT2-16C-B | Recombinant Cynomolgus Monkey ACOT2 Protein Pre-coupled Magnetic Beads | HEK293 | Cynomolgus |
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| ACOT2-583HF | Recombinant Full Length Human ACOT2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 483 amino acids |
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Involved Pathway
Acot2 involved in several pathways and played different roles in them. We selected most pathways Acot2 participated on our site, such as Biosynthesis of unsaturated fatty acids,Fatty Acyl-CoA Biosynthesis,Fatty acid elongation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Acot2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ADH1,AGPHD1,IDH3A,PGP,COX7B2,PCK1,CECR1A,ETNK1,MTMR1B,MAPK1IP1L |
| Metabolism | GRX2,GLYAT,CKMB,PDP2,AGPAT6,COQ6,CES1,ACOT11A,DGAT1B,PTGDSA |
| Fatty acid, triacylglycerol, and ketone body metabolism | ACOT13,SREBF2,ELOVL1A,ECI1,ACOT6,ABCA1,MED10,CDK19,ACOT11B,ACOT11 |
| Metabolism of lipids and lipoproteins | ACOT9.2,TMEM195,ACOT11A,FA2H,APOF,CYP2R1,ACOT9.1,Agmo,CYP24A1,PPM1LA |
| Fatty Acyl-CoA Biosynthesis | SLC25A1,ACOT11,ELOVL1A,SLC25A1A,ACOT7,ACOT13,ACOT10,ACOT9.2,ACOT9.1,ACOT6 |
| Biosynthesis of unsaturated fatty acids | TECRB,HSD17B12A,PTPLA,ELOVL6,HADHA,ELOVL2,FADS1,ELOVL5,ACOT7,SCD |
| Ovarian steroidogenesis | CYP2J6,FSHB,FSHR,PLA2G4C,INSR,INS,INS2,GNAS,BMP15,BMP6 |
| Fatty acid elongation | PPT2,TECR,HSD17B12B,ELOVL1,TECRB,ELOVL1B,MECR,ELOVL7A,ACOT1,ELOVL3 |
Protein Function
Acot2 has several biochemical functions, for example, acyl-CoA hydrolase activity,carboxylic ester hydrolase activity,palmitoyl-CoA hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Acot2 itself. We selected most functions Acot2 had, and list some proteins which have the same functions with Acot2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acyl-CoA hydrolase activity | ACOT1,ACOT10,ACOT11,ACOT5,ACSBG2,ACOT8 |
| receptor binding | HSD17B4,PPY,TNFSF8,PVRL1,CADM1,CTNND1,FGF11,TMED1,HILPDA,MYO1C |
| carboxylic ester hydrolase activity | ACOT7,ABHD2A,AADACL4,ABHD2B,LIPCA,ESD,FAM135A,ACOT6,NCEH1,ACOT8 |
| palmitoyl-CoA hydrolase activity | ACOT7,THEM4,ACOT5,ACOT1,GNPAT,BAAT,THEM5,PPT1,ACOT8 |
Interacting Protein
Acot2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Acot2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Acot2.
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References
- Yamada, J; Kurata, A; et al. Purification, molecular cloning, and genomic organization of human brain long-chain acyl-CoA hydrolase. JOURNAL OF BIOCHEMISTRY 126:1013-1019(1999).
- Maloberti, P; Lozano, RC; et al. Concerted regulation of free arachidonic acid and hormone-induced steroid synthesis by acyl-CoA thioesterases and acyl-CoA synthetases in adrenal cells. EUROPEAN JOURNAL OF BIOCHEMISTRY 269:5599-5607(2002).
