ACOT12
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Official Full Name
acyl-CoA thioesterase 12 -
Synonyms
ACOT12;acyl-CoA thioesterase 12;acyl-coenzyme A thioesterase 12;Cach;StAR related lipid transfer (START) domain containing 15;STARD15;THEAL;hCACH-1;cytosolic acetyl-CoA hydrolase;acyl-CoA thioester hydrolase 12;START domain-containing protein 15
Recombinant Proteins
- Human
- Rat
- Mouse
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACOT12-168H | Recombinant Human ACOT12 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ACOT12-457R | Recombinant Rat ACOT12 Protein | Mammalian Cell | Rat | His |
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| ACOT12-9090HCL | Recombinant Human ACOT12 293 Cell Lysate | HEK293 | Human | Non |
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| ACOT12-113R | Recombinant Rat ACOT12 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ACOT12-113R-B | Recombinant Rat ACOT12 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Acot12-1498M | Recombinant Mouse Acot12 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| ACOT12-3440H | Recombinant Human ACOT12 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| ACOT12-785HF | Recombinant Full Length Human ACOT12 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 555 amino acids |
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Involved Pathway
ACOT12 involved in several pathways and played different roles in them. We selected most pathways ACOT12 participated on our site, such as Fatty Acyl-CoA Biosynthesis,Fatty acid, triacylglycerol, and ketone body metabolism,Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACOT12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | SCP2B,SREBF2,CYP3C1,ATP5S,FIG4,ARSH,SPTLC1,ADK,CPNE1,PLBD1 |
| Metabolism of lipids and lipoproteins | ECI1,ARSH,AWAT1,ARV1,PPM1L,MED22,ALOX5AP,CYP2N13,CYP27B1,TPTE |
| Fatty acid, triacylglycerol, and ketone body metabolism | CPT1B,MED7,MED9,G0S2,MED25,CDK19,MED31,MED20,DECR1,DGAT1B |
| Triglyceride Biosynthesis | ACOT9.2,ACOT9,SLC25A1A,Agmo,ACOT11B,TMEM195,DGAT1B,ACSF2,ELOVL1A,ACOT6 |
| Pyruvate metabolism | ALDH9A1A.1,LDHAL6A,PDHA1A,PDP2,PKLR,BRP44,PKMB,PKM,PCXB,PDK3B |
| Fatty Acyl-CoA Biosynthesis | ACOT9.2,ACOT8,ACOT9,ELOVL1A,THEM5,ACOT7,SLC25A1A,ACSF2,ACOT2,ACSF3 |
Protein Function
ACOT12 has several biochemical functions, for example, ATP binding,acetyl-CoA hydrolase activity,carboxylic ester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACOT12 itself. We selected most functions ACOT12 had, and list some proteins which have the same functions with ACOT12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acetyl-CoA hydrolase activity | ACOT9,NUDT7 |
| carboxylic ester hydrolase activity | LIPI,ABHD2,LIPCA,ACOT1,ACOT9,CES1C,ACOT6,AADACL2,ABHD4,FAM135B |
| lipid binding | FAM123C,FABP6,LTC4S,UNC119.1,ACBD7,ACOT11A,CPTP,PPP5C,FABP11B,PFN3 |
| ATP binding | TAP1,PFTK1,KIF11,NOLC1,PBK,SKIV2L2,HSP90AA1.1,MOK,CAMK2G1,SUPV3L1 |
Interacting Protein
ACOT12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACOT12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACOT12.
Resources
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References
- Liu, XP; Yu, HY; et al. Biosynthesis of butenoic acid through fatty acid biosynthesis pathway in Escherichia coli. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 99:1795-1804(2015).
- Nguyen, HT; Park, H; et al. Redirection of metabolic flux for high levels of omega-7 monounsaturated fatty acid accumulation in camelina seeds. PLANT BIOTECHNOLOGY JOURNAL 13:38-50(2015).
