ackr4
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Official Full Name
Recombinant Proteins
- Human
- Bovine
- Mus musculus
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- E.coli
- Non
- GST
- His
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ACKR4-0702H | Recombinant Human ACKR4 Protein | Wheat Germ | Human | Non |
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| ACKR4-0703H | Recombinant Human ACKR4 Protein, GST-Tagged | Wheat Germ | Human | GST |
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| ACKR4-171HCL | Recombinant Human ACKR4 lysate | HEK293 | Human | Non |
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| ACKR4-3035HF | Recombinant Full Length Human ACKR4 Protein | In Vitro Cell Free System | Human | Full L. 355 amino acids |
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| ACKR4-3036HF | Recombinant Full Length Human ACKR4 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 350 amino acids |
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| RFL21817BF | Recombinant Full Length Bovine C-C Chemokine Receptor Type 11(Ccrl1) Protein, His-Tagged | E.coli | Bovine | His | Full L. Full Length (1-350) |
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| RFL30267MF | Recombinant Full Length Mouse C-C Chemokine Receptor Type 11(Ccrl1) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-350) |
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| RFL33164HF | Recombinant Full Length Human C-C Chemokine Receptor Type 11(Ccrl1) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-350) |
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Involved Pathway
ackr4 involved in several pathways and played different roles in them. We selected most pathways ackr4 participated on our site, such as Chemokine receptors bind chemokines,Class A/1 (Rhodopsin-like receptors),GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with ackr4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signaling by GPCR | CCL35.2,ARHGEF25,ARHGEF1B,CCRL2,UTS2,TAAR1,NMBA,PRKCHB,GHRH,PROK2 |
| GPCR ligand binding | KEL,PTH2,GPR4,ADORA2B,SSTR5,GPR17,NTS,GPBAR1,RGR,GPR37B |
| GPCRs, Class A Rhodopsin-like | DRD3,SSTR3,CCR8,GPR18,ADORA3,CYSLTR1,GPR68,SSTR5,OPN1MW,OR10A5 |
| Peptide ligand-binding receptors | GPR37L1,QRFP,CCL35.2,GAL,EDN2,CCL19A.2,APLNR,CXCR7B,EDNRAB,CCRL2 |
| Chemokine receptors bind chemokines | CCR7,CXCR6,CXCL11.8,CCR6,AMCF-II,CXCR7B,CCR3,CCR1,CCR5,CCBP2 |
| Class A/1 (Rhodopsin-like receptors) | CXCR7B,OXTRL,KEL,PNOC,OPN5,AGTR2,CCRL2,OXGR1,ADORA2A,KISS1 |
| Signal Transduction | BCL9L,KIF7,CGNB,SRY,ARHGAP4,CIT,DZIP1,GPR177,PCSK5,ARHGAP15 |
Protein Function
ackr4 has several biochemical functions, for example, chemokine binding,chemokine receptor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ackr4 itself. We selected most functions ackr4 had, and list some proteins which have the same functions with ackr4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chemokine binding | ACKR3B,CXCR3,PLP2 |
| chemokine receptor activity | CCR1,CXCR3,RGRA,CCBP2,CCR1L1,CCR12A,GPR17,XCR1,CCR9,CXCR3.2 |
| scavenger receptor activity | TMPRSS2,SCARF1,LOXL2B,SCART1,PRSS7,POLR1B,TMPRSS4A,LOXL4,SUSD2,PRG4B |
| protein binding | VAPB,NAE1,GTPBP4,CCDC9,ORC4L,ADRBK1,WAPAL,KLHL2,ARMC9,MAZ |
Interacting Protein
ackr4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ackr4 here. Most of them are supplied by our site. Hope this information will be useful for your research of ackr4.
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References
- Yoshie, O; Matsushima, K; et al. CCR4 and its ligands: from bench to bedside. INTERNATIONAL IMMUNOLOGY 27:11-20(2015).
- Zabel, BA; Rott, A; et al. Leukocyte Chemoattractant Receptors in Human Disease Pathogenesis. ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 10:51-81(2015).
