ACAP2
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Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 -
Overview
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 is a protein that in humans is encoded by the ACAP2 gene. -
Synonyms
ACAP2;ArfGAP with coiled-coil, ankyrin repeat and PH domains 2;centaurin, beta 2 , CENTB2;arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2;CNT B2;KIAA0041;ACAP 2;Arf GAP with coiled coil ANK repeat and PH domains 2;CENT B 2;Centaurin beta2;CENTB 2;CENTB2;Cntb2;Similar to yeast ZINC FINGER PROTEIN GCS1;centaurin-beta-2;centaurin, beta 2;OTTHUMP00000208844;Arf GAP with coiled coil, ANK repeat and PH domains 2;CNT-B2
Recombinant Proteins
- Human
- Mouse
- Chicken
- Rhesus macaque
- Rat
- Zebrafish
- E.coli
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ACAP2 involved in several pathways and played different roles in them. We selected most pathways ACAP2 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | ZFYVE9,PSD2,TGFB1,PIP5K1AA,RAB11A,VPS26A,HSPA1A,WASH1,FGFR3,SH3GLB2B |
Protein Function
ACAP2 has several biochemical functions, for example, GTPase activator activity,Rab GTPase binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACAP2 itself. We selected most functions ACAP2 had, and list some proteins which have the same functions with ACAP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTPase activator activity | RASAL3,TBC1D26,RGS21,NCKAP1L,RGS2,BAI3,ARHGAP17,WNT11,RGS5,ARHGAP36 |
| metal ion binding | ADAMTS12,ATP2C2,EGR2B,PRDM8B,ZNF584,MARCH11,ASAP2A,ZMYM2,ZFP41,OAS2 |
| Rab GTPase binding | RHOBTB3,RIMS1,RABGAP1,SGSM3,MYRIP,STX4A,ZFP652,ZFYVE20,RIN3,NSF |
Interacting Protein
ACAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ACAP2.
HSPB1;pi3p;k1_vaccw;PDK3;Tgs1;Naa10
Resources
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References
- Miyamotoa, Y; Yamamori, N; et al. Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. MOLECULAR BIOLOGY OF THE CELL 25:1532-1542(2014).
- Hong, JY; Liu, X; et al. Genetic Aberrations in Imatinib-Resistant Dermatofibrosarcoma Protuberans Revealed by Whole Genome Sequencing. PLOS ONE 8:-(2013).
