ACADS
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Official Full Name
acyl-CoA dehydrogenase, C-2 to C-3 short chain; SCAD -
Overview
This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. [provided by RefSeq, Jul 2008] -
Synonyms
ACADS;acyl-CoA dehydrogenase, C-2 to C-3 short chain;SCAD;ACAD3;short-chain specific acyl-CoA dehydrogenase, mitochondrial;butyryl-CoA dehydrogenase;unsaturated acyl-CoA reductase;short-chain acyl-CoA dehydrogenase;acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain;mitochondrial short-chain specific acyl-CoA dehydrogenase
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- HEK293T
- In Vitro Cell Free System
- His
- GST
- His&T7
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
ACADS involved in several pathways and played different roles in them. We selected most pathways ACADS participated on our site, such as Fatty acid degradation,Valine, leucine and isoleucine degradation,Butanoate metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACADS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Valine, leucine and isoleucine degradation | HIBADHB,AACS,IL4I1,ACADM,AOX4,HMGCL,OXCT2A,HSD17B10,HIBCH,HADHAA |
| Fatty acid metabolism | HSD17B12A,PTPLAD2,MECR,ACSL4A,Scd1,CPT1A,SCD5,ACAA1,ACSL3B,ACSL1B |
| Carbon metabolism | ACSS1,GOT2B,ENO1B,HK2,GPT2,TPI1B,ACO2,TPI1,ME1,HIBCH |
| Butanoate metabolism | AACS,HADHAB,ACAT1,ACSM1,DHRS13L1,ECHS1,HMGCS2,ABAT,OXCT1A,OXCT1 |
| Fatty acid degradation | ECI2,ACSL1B,ACSL4A,ACAA1,HADHA,GCDHB,HADH,ALDH3A2A,ACOX1,CYP4A11 |
| Metabolic pathways | ALOX5,NAT,FLAD1,B3GALT4,UPB1,SC5D,PIGV,CSAD,HSD17B6,LIPT2 |
Protein Function
ACADS has several biochemical functions, for example, acyl-CoA dehydrogenase activity,butyryl-CoA dehydrogenase activity,electron carrier activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ACADS itself. We selected most functions ACADS had, and list some proteins which have the same functions with ACADS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| fatty-acyl-CoA binding | ACBD5B,ACBD3,GCDH,ACADSB,ACOX3,ACOXL,ACBD6,ACAD9,ECI2,ACOT7 |
| flavin adenine dinucleotide binding | ACOX3,ACADL,TXNRD1,ACADVL,MTO1,DHCR24,ACAD9,GFER,NOS3,KDM1A |
| acyl-CoA dehydrogenase activity | ACOX1,ACOX3,ACADVL,GCDHA,ACADSB,ACOX2,ACOXL,ACADL,ACAD8,ETFA |
| electron carrier activity | HSD17B6,FDX1,GRXCR1,NDUFV2,AKR1B1,UQCR11,TSTA3,ACADVL,NDUFS2,AKR1C4 |
Interacting Protein
ACADS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACADS here. Most of them are supplied by our site. Hope this information will be useful for your research of ACADS.
IRF7;E2F3
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