ABCC12
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Official Full Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 12 -
Overview
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. -
Synonyms
ABCC12;ATP-binding cassette, sub-family C (CFTR/MRP), member 12;multidrug resistance-associated protein 9;MRP9;ATP-binding cassette sub-family C member 12;ATP-binding cassette transporter sub-family C member 12;MGC27071
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ABCC12-1099M | Recombinant Mouse ABCC12 Protein | Mammalian Cell | Mouse | His |
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| ABCC12-403R | Recombinant Rat ABCC12 Protein | Mammalian Cell | Rat | His |
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| ABCC12-196M | Recombinant Mouse ABCC12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ABCC12-196M-B | Recombinant Mouse ABCC12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| ABCC12-58R | Recombinant Rat ABCC12 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| ABCC12-58R-B | Recombinant Rat ABCC12 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
ABCC12 involved in several pathways and played different roles in them. We selected most pathways ABCC12 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCC12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCD3A,Abcb1b,ABCB3L1,ABCC9,ABCB1LB,ABCA8,ABCC1,SUR2A,ABCB4,ABCG1 |
Protein Function
ABCC12 has several biochemical functions, for example, ATP binding,ATPase activity,ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCC12 itself. We selected most functions ABCC12 had, and list some proteins which have the same functions with ABCC12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase activity, coupled to transmembrane movement of substances | ABCG2A,ABCG8,ABCC3,ABCA7,ABCA9,ABCC1,Abca2,ABCA13,ABCD3B,DPY19L2 |
| nucleotide binding | DCKL1B,ARL8BA,NSFB,GUCY2E,EIF2S3Y,MAP2K2A,HNRNPA2B1,NUBP1,RAC3A,EGFRA |
| ATPase activity | PSMC3,BLM,MACF1,PICK1,KIF3C,ATAD1A,ERCC3,Abca2,SWSAP1,ATAD1B |
| ATP binding | FAM20B,SPHK1,ATP6V1BA,MAP3K4,SYN1,OASL1,MASTL,MAPK3,CSF1RA,EPHB2B |
Interacting Protein
ABCC12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCC12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCC12.
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