ABCA9
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Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 9 -
Overview
This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two transmembrane domains and two nucleotide binding folds. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This gene is a member of the ABC1 subfamily and is clustered with four other ABC1 family members on chromosome 17q24. Transcriptional expression of this gene is induced during monocyte differentiation into macrophages and is suppressed by cholesterol import. -
Synonyms
ABCA9;ATP-binding cassette, sub-family A (ABC1), member 9;ATP-binding cassette sub-family A member 9;EST640918;ATP binding cassette A9;ATP binding cassette sub family A (ABC1) member 9;ATP binding cassette sub family A member 9;DKFZp686F2450;MGC75415;ATP-binding cassette A9
Recombinant Proteins
- Human
- Mouse
- Rat
- E. coli
- Mammalian Cell
- E.coli
- HEK293
- N-GST
- N-His
- His
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ALS2CR8-9603H | Recombinant Human ALS2CR8 protein, GST-tagged | E. coli | Human | N-GST | 1-311 aa | |
| CD1D-10920H | Recombinant Human CD1D protein, His-tagged | E. coli | Human | N-His | 18-302 aa | |
| ABCA9-1086M | Recombinant Mouse ABCA9 Protein | Mammalian Cell | Mouse | His |
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| ABCA9-8144H | Recombinant Human ABCA9 protein, His & T7-tagged | E.coli | Human | His&T7 | Glu1423~Leu1590 |
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| Abca9-8145M | Recombinant Mouse Abca9 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Glu1422~Leu1589 |
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| Abca9-8146R | Recombinant Rat Abca9 protein, His & T7-tagged | E.coli | Rat | His&T7 | Glu1416~Leu1583 |
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| ABCA9-185M | Recombinant Mouse ABCA9 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ABCA9-185M-B | Recombinant Mouse ABCA9 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ABCA9 involved in several pathways and played different roles in them. We selected most pathways ABCA9 participated on our site, such as ABC transporters, which may be useful for your reference. Also, other proteins which involved in the same pathway with ABCA9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ABC transporters | ABCA1,ABCG2,ABCA1B,ABCA7,ABCC4,TAP1,TAP2,ABCD3A,ABCD3,ABCB6A |
Protein Function
ABCA9 has several biochemical functions, for example, ATP binding,ATPase activity,ATPase activity, coupled to transmembrane movement of substances. Some of the functions are cooperated with other proteins, some of the functions could acted by ABCA9 itself. We selected most functions ABCA9 had, and list some proteins which have the same functions with ABCA9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | ATP6V1AA,TAP1,TRPM6,CKB,KIFC2,KIF14,ATP1A3B,PIM1,PIK3CB,DYRK1A |
| nucleotide binding | GSK3AA,DGKAA,CAMK2D1,NPR1A,NME2B.2,UBE2NB,ARL3L2,SNRPB2,RAB11BB,RHOGA |
| ATPase activity, coupled to transmembrane movement of substances | ABCB8,ABCA8,ABCC8,ABCA1,ABCG2A,Abca2,ABCC10,ABCA4,ABCD4,ABCC11 |
| ATPase activity | ABCG4B,EIF4A1B,ABCA13,DNAHC8,PMS1,KIF20A,EIF4A1A,ABCD3,ABCC5,ABCA4A |
| transporter activity | DYF-1,SLC2A9L1,RBP7B,HIATL2,SLC2A15A,SEC14L2,XK,CRABP1A,MUP17,HIATL1 |
Interacting Protein
ABCA9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABCA9 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABCA9.
Resources
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References
- Thiel, CS; Hauschild, S; et al. Identification of Reference Genes in Human Myelomonocytic Cells for Gene Expression Studies in Altered Gravity. Biomed Research International :-(2015).
- Hedditch, EL; Gao, B; et al. ABCA Transporter Gene Expression and Poor Outcome in Epithelial Ovarian Cancer. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 106:-(2014).
