ZP2
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Official Full Name
zona pellucida glycoprotein 2 (sperm receptor) -
Synonyms
ZP2;zona pellucida glycoprotein 2 (sperm receptor);zona pellucida sperm-binding protein 2;zona pellucida protein A;zona pellucida glycoprotein ZP2;ZPA;Zp-2
Recombinant Proteins
- Cynomolgus
- Mouse
- Chicken
- Rat
- Human
- Dog
- Macaca radiata (Bonnet macaque)
- Sus scrofa (Pig)
- Mus musculus
- Mammalian Cell
- E.coli
- HEK293
- E.coli expression system
- HEK293T
- His
- His&T7
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
ZP2 involved in several pathways and played different roles in them. We selected most pathways ZP2 participated on our site, such as Fertilization,Interaction With The Zona Pellucida,Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Reproduction | CATSPER3,TMEM146,CATSPERB,ADAM2,CATSPER2,ADAM21,CATSPERG1,IZUMO4,IZUMO1,ADAM20 |
| Interaction With The Zona Pellucida | OVGP1,ZP3,ADAM20,ADAM2,ADAM21,ADAM30 |
| Fertilization | ADAM20,ADAM2,CATSPERB,CATSPER1,ZP3,Acr,HVCN1,TMEM146,ADAM30,CATSPERG2 |
| Ovarian Infertility Genes | SYNE2,DMC1,DAZL,NR5A1,ZP3,NRIP1,GJA4,MSH5,INHA |
Protein Function
ZP2 has several biochemical functions, for example, acrosin binding,coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ZP2 itself. We selected most functions ZP2 had, and list some proteins which have the same functions with ZP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| coreceptor activity | CXCR6,RGMA,ACKR3B,RGMD,RAMP3,ACVR2A,CXCR4,CXCR7B,PVRL1,LY96 |
| acrosin binding | SERPINA5,ZP3 |
Interacting Protein
ZP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZP2.
SRC;PLCG1
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References
- Petit, FM; Serres, C; et al. Moonlighting proteins in sperm-egg interactions. BIOCHEMICAL SOCIETY TRANSACTIONS 42:1740-1743(2014).
- Avella, MA; Baibakov, B; et al. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. JOURNAL OF CELL BIOLOGY 205:801-809(2014).
