ZNF197
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Official Full Name
zinc finger protein 197 -
Overview
This gene product belongs to the zinc finger protein superfamily, members of which are regulatory proteins characterized by nucleic acid-binding zinc finger domains. The encoded protein contains 20 tandemly arrayed C2H2-type zinc fingers, a Kruppel-associated box (KRAB) domain, and a SCAN box. This transcript turns over rapidly and contains 3 UTR AUUUA motifs, which are often a hallmark of rapid turnover. It is overexpressed in some thyroid papillary carcinomas. This gene is located in a cluster of zinc finger genes at 3p21. Two alternatively spliced transcripts encoding different isoforms have been described. -
Synonyms
ZNF197;zinc finger protein 197;zinc finger protein 166 , ZNF166;D3S1363E;P18;ZKSCAN9;VHL associated KRAB A domain containing protein;VHLaK;ZNF166;ZNF20;OTTHUMP00000164119;Zinc finger protein 166;Zinc finger protein 20;Zinc finger protein with KRAB and SCAN domains 9;OTTHUMP00000209715;OTTHUMP00000209717;OTTHUMP00000209718;VHL-associated KRAB-A domain-containing protein
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Involved Pathway
ZNF197 involved in several pathways and played different roles in them. We selected most pathways ZNF197 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF197 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
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Protein Function
ZNF197 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF197 itself. We selected most functions ZNF197 had, and list some proteins which have the same functions with ZNF197. You can find most of the proteins on our site.
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Interacting Protein
ZNF197 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF197 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF197.
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References
- Haralambieva, IH; Oberg, AL; et al. High-Dimensional Gene Expression Profiling Studies in High and Low Responders to Primary Smallpox Vaccination. JOURNAL OF INFECTIOUS DISEASES 206:1512-1520(2012).
