ZNF157
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Official Full Name
zinc finger protein 157 -
Overview
This gene product is a likely zinc finger family transcription factor. It contains KRAB-A and KRAB-B domains that act as transcriptional repressors in related proteins, and multiple zinc finger DNA binding motifs and finger linking regions characteristic of the Kruppel family. This gene is part of a gene cluster on chromosome Xp11.23. -
Synonyms
ZNF157;zinc finger protein 157;zinc finger protein 157 (HZF22);HZF22;Zinc finger protein 22;zinc finger protein HZF22
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZNF157-1989HCL | Recombinant Human ZNF157 cell lysate | Human | Non |
|
Involved Pathway
ZNF157 involved in several pathways and played different roles in them. We selected most pathways ZNF157 participated on our site, such as Gene Expression,Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF157 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Generic Transcription Pathway | ZNF398,ZNF688,ZNF317,ZFP2,Txn1,ZNF705A,ZNF436,ZNF302,ZNF684,JUNB |
| Gene Expression | SNUPN,PSTPIP2,MTA1,NR1I3,TRMT44,ZNF334,ADAT1,KRBA1,NR2F6A,NR2C2 |
Protein Function
ZNF157 has several biochemical functions, for example, DNA binding,metal ion binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF157 itself. We selected most functions ZNF157 had, and list some proteins which have the same functions with ZNF157. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | TEFB,RAB11FIP4A,POU5F1,MYCLA,ZNF691,POU6F1,IRF6,ZFP12,DMRT2A,TCF3A |
| DNA binding | NKX2.5,DHX58,MYCB,ZFP36L3,ZBTB37,MTERFD1,HIST1H2AD,ZNF711,FUS,FOXN2B |
| metal ion binding | AGAP5,NUBPL,COL1A2,PDE12,ZNF829,MICALL2A,GGPS1,ZBTB7B,CLCA1,KLF7B |
Interacting Protein
ZNF157 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF157 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF157.
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References
- Wang, XK; Ji, W; et al. Identification of two novel GATA6 mutations in patients with nonsyndromic conotruncal heart defects. MOLECULAR MEDICINE REPORTS 10:743-748(2014).
- Ishikura, S; Ogawa, M; et al. Zfat-Deficient CD4(+)CD8(+) Double-Positive Thymocytes Are Susceptible to Apoptosis With Deregulated Activation of p38 and JNK. JOURNAL OF CELLULAR BIOCHEMISTRY 116:149-157(2015).
