ZNF12
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Official Full Name
zinc finger protein 12 -
Overview
This gene is a member of the krueppel C2H2-type zinc-finger protein family and encodes a protein with eight C2H2-type zinc fingers and a KRAB domain. This nuclear protein is involved in developmental control of gene expression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. -
Synonyms
ZNF12;zinc finger protein 12;zinc finger protein 325 , ZNF325;GIOT 3;KOX3;GIOT3;Gonadotropin inducible transcription repressor 3;Zinc finger protein 325;Zinc finger protein KOX3;ZNF325;zinc finger protein 11;gonadotropin-inducible ovary transcription repressor 3;HZF11;GIOT-3;Krox-7;Zfp-12;C530015C18
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZNF12-3815H | Recombinant Human ZNF12, His-tagged | E.coli | Human | His | 93-156aa | |
| ZFP12-18827M | Recombinant Mouse ZFP12 Protein | Mammalian Cells | Mouse | His |
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| ZNF12-10397M | Recombinant Mouse ZNF12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ZNF12-10397M-B | Recombinant Mouse ZNF12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ZNF12 involved in several pathways and played different roles in them. We selected most pathways ZNF12 participated on our site, such as Gene Expression,Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Gene Expression | KRBOX4,METTL3,NRBF2B,ZNF577,NR2F6,TNRC6B,ZNF484,ZNF560,ZFP36L1A,ZNF584 |
| Generic Transcription Pathway | ZNF43,LAMTOR1,MED25,ZNF740,MED16,RARAB,MED13B,ZNF460,ZNF274,ZNF764 |
Protein Function
ZNF12 has several biochemical functions, for example, DNA binding,metal ion binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF12 itself. We selected most functions ZNF12 had, and list some proteins which have the same functions with ZNF12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | TBX10,KLF4,TRIM22,ZNF493,TSC22D4,GLI3,DLX3,ZNF8,NFYA,ZNF334 |
| metal ion binding | SMG1,CYP2C54,FOLH1,NDUFV1,NME3,NUDT14,BIRC5,COX5B,ZNF187,DOHH |
| DNA binding | TBPL1,NR1H2,ZNF738,ZNF2,RAD51L3,SETDB1,REV3L,CHD2,GPBP1L1,HIST1H3C |
Interacting Protein
ZNF12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF12 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF12.
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References
- Ripoll, VM; Lambrianides, A; et al. Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome. BLOOD 124:3808-3816(2014).
- Jackson, R; Braubach, OR; et al. Expression of sall4 in taste buds of zebrafish. DEVELOPMENTAL NEUROBIOLOGY 73:543-558(2013).
