ZHX3
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Official Full Name
zinc fingers and homeoboxes 3 -
Overview
This gene encodes a member of the zinc fingers and homeoboxes (ZHX) gene family. The encoded protein contains two C2H2-type zinc fingers and five homeodomains and forms a dimer with itself or with zinc fingers and homeoboxes family member 1. In the nucleus, the dimerized protein interacts with the A subunit of the ubiquitous transcription factor nuclear factor-Y and may function as a transcriptional repressor. -
Synonyms
ZHX3;zinc fingers and homeoboxes 3;TIX1, triple homeobox 1;zinc fingers and homeoboxes protein 3;KIAA0395;triple homeobox 1;triple homeobox protein 1;zinc finger and homeodomain protein 3;TIX1
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Zebrafish
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
- Avi&His&Fc
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZHX3-3721H | Recombinant Human ZHX3 protein, GST-tagged | E.coli | Human | GST | 848-956 aa | |
| ZHX3-5293R | Recombinant Rhesus monkey ZHX3 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| ZHX3-6707R | Recombinant Rat ZHX3 Protein | Mammalian Cells | Rat | His |
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| ZHX3-9847Z | Recombinant Zebrafish ZHX3 | Mammalian Cells | Zebrafish | His |
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| ZHX3-1983HCL | Recombinant Human ZHX3 cell lysate | Human | Non |
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| ZHX3-5106R | Recombinant Rhesus Macaque ZHX3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| ZHX3-5106R-B | Recombinant Rhesus Macaque ZHX3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| ZHX3-6339R | Recombinant Rat ZHX3 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&His&Fc |
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| ZHX3-6339R-B | Recombinant Rat ZHX3 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Zhx3-7108M | Recombinant Mouse Zhx3 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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Involved Pathway
ZHX3 involved in several pathways and played different roles in them. We selected most pathways ZHX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZHX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
ZHX3 has several biochemical functions, for example, DNA binding,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX3 itself. We selected most functions ZHX3 had, and list some proteins which have the same functions with ZHX3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | PGR,SETDB1B,POLR3D,FOXI3A,ARID5B,OTX1A,ARID3C,NFYA,IFT57,HIST3H3 |
| metal ion binding | PFKP,RASA3,PAPOLB,MYLIPB,KLK4,CYP7A1A,ZNF557,DNAJA2,PVALB2,ZNF615 |
| protein homodimerization activity | CEACAM5,ECT2,CHMP1A,GJC3,TCF12,AMBP,UGT1A7,NKX2-5,Fzd4,PARK7 |
| transcription corepressor activity | DR1,LOXL2,HIPK2,RELB,ID4,NR0B2,KDM5B,AES,TGIF1,C1D |
| protein binding | ERGIC2,CCL3,RPL19,CLNS1A,RASSF9,RPP25L,SULT2B1,SYCE3,CCDC22,CFL2 |
| protein heterodimerization activity | CEBPE,SIM2,EXT1,SOX8,NR4A1,TAF6,ERBB3,CASP8,UBA3,HIST3H2A |
| transcription factor activity, sequence-specific DNA binding | RELB,PRDM2,PPARAA,MLXIPL,INSM1B,INSM1A,DLX6,SMAD2,PLAG1,PRDM1A |
Interacting Protein
ZHX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX3.
NLK;ATXN1;q8ckl9_yerpe;q9wmx2-pro_0000037548;mdm2_human_probe
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References
- Chaudhry, P; Fabi, F; et al. Prostate apoptosis response-4 mediates TGF-beta-induced epithelial-to-mesenchymal transition. CELL DEATH & DISEASE 5:-(2014).
- Lee, JH; Nam, H; et al. Upregulation of GM-CSF by TGF-beta 1 in epithelial mesenchymal transition of human HERS/ERM cells. IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL 50:399-405(2014).
