ZFYVE16
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Official Full Name
zinc finger, FYVE domain containing 16 -
Overview
The ZFYVE16 gene encodes endofin, an endosomal protein implicated in regulating membrane trafficking. It is;characterized by the presence of a phosphatidylinositol 3-phosphate-binding FYVE domain positioned in the middle of;the molecule (Seet et al., 2004 (PubMed 14613930)). -
Synonyms
ZFYVE16;zinc finger, FYVE domain containing 16;zinc finger FYVE domain-containing protein 16;endofin;KIAA0305;PPP1R69;protein phosphatase 1;regulatory subunit 69;B130024H06Rik;B130031L15;DKFZp686E13162;mKIAA0305;AI035632;Endosomal associated FYVE domain protein;Endosome associated FYVE domain protein;OTTMUSP00000029589;RGD1564784;Zinc finger FYVE domain containing protein 16;OTTHUMP00000135318;OTTHUMP00000222226;OTTHUMP00000222227;endosome-associated FYVE domain protein;endosome-associated FYVE-domain protein;protein phosphatase 1, regulatory subunit 69
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ZFYVE16-3804H | Recombinant Human ZFYVE16, GST-tagged | E.coli | Human | GST | N-term-306aa | |
| ZFYVE16-19163M | Recombinant Mouse ZFYVE16 Protein | Mammalian Cells | Mouse | His |
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| ZFYVE16-1979HCL | Recombinant Human ZFYVE16 cell lysate | Human | Non |
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| ZFYVE16-10369M | Recombinant Mouse ZFYVE16 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ZFYVE16-10369M-B | Recombinant Mouse ZFYVE16 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
ZFYVE16 involved in several pathways and played different roles in them. We selected most pathways ZFYVE16 participated on our site, such as Endocytosis,TGF-beta signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFYVE16 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | DNAJC6,PARD6GB,RAB11FIP2,CXCR4A,RAB5AB,RAB11FIP3,RHOAA,STAM2,GIT2,GRK7 |
| TGF-beta signaling pathway | BMP4,PPP2CA,SMAD2,LEFTY2,ACVR1B,RPS6KB2,BMP5,GDF7,SMURF2,CHRD |
Protein Function
ZFYVE16 has several biochemical functions, for example, 1-phosphatidylinositol binding,metal ion binding,phosphatidylinositol-3,4,5-trisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFYVE16 itself. We selected most functions ZFYVE16 had, and list some proteins which have the same functions with ZFYVE16. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | CYP3C1L2,ZBED2,Amy1,NR1H5,ZFP451,ASPHD2,ZNF410,DDAH1,CYP2K22,Alb |
| 1-phosphatidylinositol binding | WDFY3,PLEKHA2,PICALM,SCARB1,ZFYVE1,ZFYVE9,PICALMB,PLEKHA4,MCF2L,EEA1 |
| protein binding | TARS,BOC,ZNF202,TMEM66,ZNF238,NFYC,RNF149,CPNE6,NUPL1,RNF111 |
| protein transporter activity | VPS26B,MLC1,IPO4,TIMM9,DPY19L2,CHMP7,USO1,AP4B1,RAMP2,RAP1A |
| phosphatidylinositol-3,4,5-trisphosphate binding | JPH2,PARD3,BTK,AKT1,ARHGAP9,PHLDA3,PIRT,ADAP2,ARAP2,ARAP3 |
Interacting Protein
ZFYVE16 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFYVE16 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFYVE16.
TOM1;EEA1;PPP1CA;pepP;RNF11;Ptpn23
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References
- Shibui, T; Kobayashi, T; et al. Isolation of cross-reacting antigen candidates by mRNA-display using a mixed cDNA library. BIOTECHNOLOGY LETTERS 30:2037-2043(2008).
