ZEB2
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Official Full Name
zinc finger E-box binding homeobox 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Zeb2-1848M | Recombinant Mouse Zeb2 protein, His-tagged | E.coli | Mouse | His | Gln962~Glu1215 | |
| ZEB2-18799M | Recombinant Mouse ZEB2 Protein | Mammalian Cell | Mouse | His |
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| ZEB2-10325M | Recombinant Mouse ZEB2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| ZEB2-10325M-B | Recombinant Mouse ZEB2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| Zeb2-1648M | Recombinant Mouse Zeb2 protein, His & T7-tagged | E.coli | Mouse | His&T7 | Gln962~Glu1215 |
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Involved Pathway
ZEB2 involved in several pathways and played different roles in them. We selected most pathways ZEB2 participated on our site, such as MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZEB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MicroRNAs in cancer | MAPK7,PDGFRB,ROCK1,CCNE2,EZR,ERBB3,GLS2,PTEN,PDCD4,SPRY2 |
Protein Function
ZEB2 has several biochemical functions, for example, DNA binding,R-SMAD binding,metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZEB2 itself. We selected most functions ZEB2 had, and list some proteins which have the same functions with ZEB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | NFE2L1,SIX3,SUB1,MEOX2,SPI1,SIX6,PROP1,POU4F1,CUX1,MIXL1 |
| DNA binding | FLI1B,H3F3B.1,ZNF446,DNA2,DRAP1,CHD2,ELK4,APP,MYO18A,POLR2K |
| metal ion binding | ENPP4,MAP2K5,LIMK1A,ZNF511,UQCRC2B,PPP2R3C,RARGB,CCC2,E4F1,ZNF256 |
| R-SMAD binding | CTNNB1,FOXH1,AXIN1,PMEPA1,SMAD6,SMURF1,RANBP3,TRIM33,C18orf1,PPM1A |
| nucleic acid binding | SPAG7,RNASEL3,RNASE2,ALYREF,ZFP143,KLF5,SAMHD1,U2AF2B,VEZF1B,GTF3A |
Interacting Protein
ZEB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZEB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZEB2.
Ywhae
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References
- Gamba, CO; Campos, LC; et al. ZEB2 and ZEB1 expression in a spontaneous canine model of invasive micropapillary carcinoma of the mammary gland. RESEARCH IN VETERINARY SCIENCE 97:554-559(2014).
- Rowe, M; Raithatha, S; et al. Counteracting Effects of Cellular Notch and Epstein-Barr Virus EBNA2: Implications for Stromal Effects on Virus-Host Interactions. JOURNAL OF VIROLOGY 88:12065-12076(2014).
