ZDHHC8
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Official Full Name
zinc finger, DHHC-type containing 8 -
Overview
This gene encodes a four transmembrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein may function as a palmitoyltransferase. Defects in this gene may be associated with a susceptibility to schizophrenia. Alternate splicing of this gene results in multiple transcript variants. A pseudogene of this gene is found on chromosome 22. -
Synonyms
ZDHHC8;zinc finger, DHHC-type containing 8;probable palmitoyltransferase ZDHHC8;KIAA1292;ZNF378;DHHC 8;DHHC domain containing 8;Membrane associated DHHC8 zinc finger protein;ZDHHCL1;Zinc finger DHHC domain containing protein 8;Zinc finger protein 378;OTTHUMP00000197629;OTTHUMP00000197630;OTTHUMP00000197631;zinc finger, DHHC domain like containing 1;membrane-associated DHHC8 zinc finger protein;DHHC8
Recombinant Proteins
- Chicken
- Rhesus macaque
- Dog
- Human
- Mus musculus
- Pan troglodytes
- Mammalian Cell
- E.coli expression system
- Wheat Germ
- HEK293
- His
- GST
- His&Fc&Avi
Involved Pathway
ZDHHC8 involved in several pathways and played different roles in them. We selected most pathways ZDHHC8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZDHHC8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
ZDHHC8 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by ZDHHC8 itself. We selected most functions ZDHHC8 had, and list some proteins which have the same functions with ZDHHC8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
ZDHHC8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZDHHC8 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZDHHC8.
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References
- Sun, Y; Hu, D; et al. Association between variants of zinc finger genes and psychiatric disorders: Systematic review and meta-analysis. SCHIZOPHRENIA RESEARCH 162:124-137(2015).
- Ota, VK; Gadelha, A; et al. ZDHHC8 gene may play a role in cortical volumes of patients with schizophrenia. SCHIZOPHRENIA RESEARCH 145:33-35(2013).
