XAGE2
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Official Full Name
X antigen family, member 2 -
Overview
This gene is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in normal testis, and in Ewings sarcoma, rhabdomyosarcoma, a breast cancer and a germ cell tumor. The protein encoded by this gene shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. -
Synonyms
XAGE2;X antigen family, member 2;G antigen, family D, 3 , GAGED3;G antigen family D member 3;cancer/testis antigen family 12;member 2;CT12.2;XAGE 2;Cancer/testis antigen 12.2;G antigen family D 3;GAGED3;Protein XAGE 2;Protein XAGE2;X antigen family member 2;XAGE 2 protein;protein XAGE-2;G antigen, family D, 3;cancer/testis antigen family 12, member 2;XAGE-2;XAGE2B
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| XAGE2-270HCL | Recombinant Human XAGE2 293 Cell Lysate | HEK293 | Human | Non |
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| XAGE2-1268HFL | Recombinant Full Length Human XAGE2 Protein, C-Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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| XAGE2-1813H | Recombinant Human XAGE2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| XAGE2-2364H | Recombinant Human XAGE2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | His&Fc&Avi |
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| XAGE2-2364H-B | Recombinant Human XAGE2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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Involved Pathway
XAGE2 involved in several pathways and played different roles in them. We selected most pathways XAGE2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with XAGE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
XAGE2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by XAGE2 itself. We selected most functions XAGE2 had, and list some proteins which have the same functions with XAGE2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ORAI1,ERH,CST7,KTN1,ARPC3,EHHADH,GTF2F1,LEMD3,NOP10,CST1 |
Interacting Protein
XAGE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XAGE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of XAGE2.
FLJ13057;GMCL1P1;TERF2IP;EPS8;EHMT2;POT1
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References
- Satofuka, H; Okabe, Y; et al. Immunization method for multi-pass membrane proteins using highly metastatic cell lines. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 450:99-104(2014).
- Menard, L; Cantaert, T; et al. Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 133:1149-1161(2014).
