Wipf1
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Official Full Name
WAS/WASL interacting protein family, member 1 -
Overview
May have direct activity on the actin cytoskeleton. Induces actin polymerization and redistribution. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation (By similarity). Plays an important role in the intracellular motility of vaccinia virus by functioning as an adapter for recruiting WASL to vaccinia virus. -
Synonyms
D2Ertd120e;Protein PRPL-2;PRPL 2;PRPL-2 protein;WAS/WASL interacting protein family member 1;WASP-interacting protein;WASPIP;WIP;Wipf1;WIPF1;Wiskott-Aldrich syndrome protein interacting protein;WAS/WASL interacting protein family, member 1
Recombinant Proteins
- Human
- Chicken
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WIPF1-3731H | Recombinant Human WIPF1, His-tagged | E.coli | Human | His | 14-238aa | |
| WIPF1-2132C | Recombinant Chicken WIPF1 | Mammalian Cell | Chicken | His |
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| WIPF1-6591R | Recombinant Rat WIPF1 Protein | Mammalian Cell | Rat | His |
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| WIPF1-311HCL | Recombinant Human WIPF1 293 Cell Lysate | HEK293 | Human | Non |
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| WIPF1-3055H | Recombinant Human WIPF1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| WIPF1-4262H | Recombinant Human WIPF1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| WIPF1-579H | Recombinant Human WIPF1 Protein, His-tagged | E.coli | Human | His | Thr24-Asn200 |
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| WIPF1-6247R | Recombinant Rat WIPF1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| WIPF1-6247R-B | Recombinant Rat WIPF1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| Wipf1-7002M | Recombinant Mouse Wipf1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
Wipf1 involved in several pathways and played different roles in them. We selected most pathways Wipf1 participated on our site, such as Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Wipf1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Endocytosis | RAB7,ASAP2,HRAS,EPN3,DNM2,ARPC5LA,CLINT1A,GRK7A,SMURF2,VPS4B |
Protein Function
Wipf1 has several biochemical functions, for example, actin binding,actin filament binding,profilin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Wipf1 itself. We selected most functions Wipf1 had, and list some proteins which have the same functions with Wipf1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CEBPA,AKAP6,PAIP1,TTC17,CDKL3,TRPV4,SERPINI2,POP7,RANBP3,WASF2 |
| profilin binding | RHOQ,PCLO,CTTN,DIAPH1,CYFIP1,HTT,EVL,DIAP1,VASP,FMNL1 |
| actin filament binding | TLN2A,ANTXR1,SSFA2,SVILA,AIF1,CTNNA3,CORO1A,VCLA,SPTA1,LCP1 |
| actin binding | PARVAB,SVILA,EPB49,TBCCD1,EPB41L3A,AFAP1,DAAM1B,ABLIM1B,SHANK3,SNTA1 |
Interacting Protein
Wipf1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Wipf1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Wipf1.
WAS;WASL
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