WHSC1L1
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Official Full Name
Wolf-Hirschhorn syndrome candidate 1-like 1 -
Overview
This gene is related to the Wolf-Hirschhorn syndrome candidate-1 gene and encodes a protein with PWWP (proline-tryptophan-tryptophan-proline) domains. The function of the protein has not been determined. Two alternatively spliced variants have been described. -
Synonyms
WHSC1L1;Wolf-Hirschhorn syndrome candidate 1-like 1;histone-lysine N-methyltransferase NSD3;FLJ20353;NSD3;DKFZp667H044;Histone lysine N methyltransferase NSD3;MGC126766;MGC142029;NSD 3;Nuclear set domain containing 3;Nuclear SET domain containing protein 3;pp14328;Whistle;WHSC1 like protein 1;WHSC1L1 protein;Wolf Hirschhorn syndrome candidate 1 like 1;protein whistle;OTTHUMP00000228478;OTTHUMP00000228479;OTTHUMP00000228480;OTTHUMP00000228487;WHSC1-like protein 1;nuclear SET domain-containing protein 3;WHSC1-like 1 isoform 9 with methyltransferase activity to lysi
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- Yeast
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WHSC1L1-3729H | Recombinant Human WHSC1L1, GST-tagged | E.coli | Human | GST | N-term-300aa | |
| WHSC1L1-148H | Recombinant Human WHSC1L1 Protein, GST-tagged | E.coli | Human | GST | 1021-1322 |
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| WHSC1L1-18546M | Recombinant Mouse WHSC1L1 Protein | Mammalian Cell | Mouse | His |
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| WHSC1L1-186H | Recombinant Human WHSC1L1 protein, GST-tagged | E.coli | Human | GST | 1021-1322 a.a. |
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| WHSC1L1-28412TH | Recombinant Human WHSC1L1, His-tagged | E.coli | Human | His | 240-645 a.a. |
|
| WHSC1L1-313HCL | Recombinant Human WHSC1L1 293 Cell Lysate | HEK293 | Human | Non |
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| WHSC1L1-314HCL | Recombinant Human WHSC1L1 293 Cell Lysate | HEK293 | Human | Non |
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| WHSC1L1-10178M | Recombinant Mouse WHSC1L1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| WHSC1L1-10178M-B | Recombinant Mouse WHSC1L1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| WHSC1L1-2631H | Recombinant Human WHSC1L1 Protein (1-645 aa), His-tagged | Yeast | Human | His | 1-645 aa |
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Involved Pathway
WHSC1L1 involved in several pathways and played different roles in them. We selected most pathways WHSC1L1 participated on our site, such as Lysine degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with WHSC1L1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Lysine degradation | SETD1BA,PIPOX,WHSC1,SETD8B,GCDH,ALDH2,ALDH7A1,ALDH3A2A,AADAT,ASH1L |
Protein Function
WHSC1L1 has several biochemical functions, for example, histone methyltransferase activity (H3-K27 specific),histone methyltransferase activity (H3-K4 specific),histone-lysine N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WHSC1L1 itself. We selected most functions WHSC1L1 had, and list some proteins which have the same functions with WHSC1L1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| zinc ion binding | CECR1,ZGLP1,CNOT4B,KAT7,ISL2,EHMT2,PPARA,CBL,KMT2E,S100A13 |
| histone methyltransferase activity (H3-K27 specific) | EHMT1,EZH2,EHMT2 |
| histone-lysine N-methyltransferase activity | WBP7,EHMT1A,SMYD2B,EZH1,SETD1B,SETD8B,SETDB1A,SMYD3,SMYD2A,EZH2 |
| protein binding | NEURL1B,ASAP2,ERCC3,MRPL20,PVR,PEX11B,PNOC,PIK3R2,HK1,C6orf211 |
| histone methyltransferase activity (H3-K4 specific) | SETD3,KMT2A,MLL5,KMT2E,WBP7,ASH1L,MLL1,SMYD1B,SETMAR,WDR82 |
Interacting Protein
WHSC1L1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WHSC1L1 here. Most of them are supplied by our site. Hope this information will be useful for your research of WHSC1L1.
MLLT6;HEL25;RAD51;SLU7;HOXC4;MNDA;ATM;DAXX
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