WFDC12
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Official Full Name
WAP four-disulfide core domain 12 -
Overview
This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. -
Synonyms
WFDC12;WAP four-disulfide core domain 12;C20orf122, chromosome 20 open reading frame 122;WAP four-disulfide core domain protein 12;dJ211D12.4;WAP2;Putative protease inhibitor WAP12;WFD12_HUMAN;Whey acidic protein 2;protease inhibitor WAP2;single WAP motif protein 2;SWAM2;C20orf122
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| WFDC12-408H | Recombinant Human WAP four-disulfide core domain 12, His-tagged | E.coli | Human | His | 24-111 a.a. |
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| WFDC12-5009H | Recombinant Human WFDC12, His-tagged | E.coli | Human | His |
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| WFDC12-5212R | Recombinant Rhesus monkey WFDC12 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| WFDC12-6586R | Recombinant Rat WFDC12 Protein | Mammalian Cell | Rat | His |
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| WFDC12-5025R | Recombinant Rhesus Macaque WFDC12 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| WFDC12-5025R-B | Recombinant Rhesus Macaque WFDC12 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| WFDC12-6242R | Recombinant Rat WFDC12 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| WFDC12-6242R-B | Recombinant Rat WFDC12 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
WFDC12 involved in several pathways and played different roles in them. We selected most pathways WFDC12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with WFDC12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
WFDC12 has several biochemical functions, for example, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by WFDC12 itself. We selected most functions WFDC12 had, and list some proteins which have the same functions with WFDC12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| serine-type endopeptidase inhibitor activity | Serpina1c,A2M,SPINK3,MUG2,SERPING1,APLP2,SERPINB10,PAPLN,SERPINA1E,SERPINA1 |
Interacting Protein
WFDC12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WFDC12 here. Most of them are supplied by our site. Hope this information will be useful for your research of WFDC12.
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