UTS2R
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Official Full Name
urotensin 2 receptor -
Overview
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. -
Synonyms
UTS2R;urotensin 2 receptor;UTR;UTR2;GPR14;UR-2-R;urotensin-2 receptor;UR-II-R;urotensin II receptor;G protein-coupled receptor 14;G-protein coupled receptor 14
Recombinant Proteins
- Rhesus macaque
- Rat
- Macaca mulatta
- Mus musculus
- Bovine
- Human
- Mammalian Cell
- E.coli expression system
- HEK293
- His
- Non
- His&Fc&Avi
Involved Pathway
UTS2R involved in several pathways and played different roles in them. We selected most pathways UTS2R participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with UTS2R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | HTR6,PRP2,DRD1A,DRD2L,LEPB,GABBR2,AVPR1A,HTR1AB,TAAR12H,VIPR1B |
Protein Function
UTS2R has several biochemical functions, for example, G-protein coupled receptor activity,urotensin II receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UTS2R itself. We selected most functions UTS2R had, and list some proteins which have the same functions with UTS2R. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-protein coupled receptor activity | RXFP2A,GPR30,PTGDR2,OPN5,GPR132B,GPR186,TAS2R117,GPR15,OR10H1,GRM6 |
Interacting Protein
UTS2R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UTS2R here. Most of them are supplied by our site. Hope this information will be useful for your research of UTS2R.
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References
- Song, N; Ding, WH; et al. Urotensin II Stimulates Vascular Endothelial Growth Factor Secretion From Adventitial Fibroblasts in Synergy With Angiotensin II. CIRCULATION JOURNAL 76:1267-1273(2012).
- Dai, HY; He, T; et al. Urotensin-2 promotes collagen synthesis via ERK1/2-dependent and ERK1/2-independent TGF-beta 1 in neonatal cardiac fibroblasts. CELL BIOLOGY INTERNATIONAL 35:93-98(2011).
