UPP1
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Official Full Name
uridine phosphorylase 1 -
Overview
The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine;phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine;and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate.;Pyrimidine nucleoside phosphorylases can add ribose or deoxyribose to pyrimidine bases to form nucleosides that can be;incorporated into RNA or DNA (Watanabe and Uchida, 1995 (PubMed 7488099)). -
Synonyms
UPP1;uridine phosphorylase 1;UP, uridine phosphorylase;UDRPASE;UPASE;UPP;UPase 1;urdPase 1;UP
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- His
- His&T7
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
UPP1 involved in several pathways and played different roles in them. We selected most pathways UPP1 participated on our site, such as Pyrimidine metabolism,Drug metabolism - other enzymes,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with UPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Drug metabolism - other enzymes | UGT2A3,GUSB,UGT1AB,UCK2A,UGT1A2,UGT1A3,UGT1A7,Nat3,UGT5G1,DPYDB |
Metabolic pathways | HSD17B6,RDH12,UROD,ITPKA,LPIN3,SPTLC2B,ST6GALNAC1,SPR,DHRS9,NDUFS3 |
Pyrimidine metabolism | DPYDA.1,AK9,NT5C2B,POLR2C,DPYS,NME7,NME6,UMPS,POLE3,POLR2J3 |
Protein Function
UPP1 has several biochemical functions, for example, uridine phosphorylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UPP1 itself. We selected most functions UPP1 had, and list some proteins which have the same functions with UPP1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
uridine phosphorylase activity | UPP2 |
Interacting Protein
UPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UPP1.
mtlA;Stmn1;VPS18
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