UGT2A3
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Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide A3 -
Synonyms
UGT2A3;UDP glucuronosyltransferase 2 family, polypeptide A3;UDP-glucuronosyltransferase 2A3;FLJ21934;UDP glucuronosyltransferase 2 family polypeptide A3;UDP glucuronosyltransferase 2A3;UDPGT 2A3
Recombinant Proteins
- Mouse
- Rhesus macaque
- Zebrafish
- Human
- Mammalian Cell
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UGT2A3-17814M | Recombinant Mouse UGT2A3 Protein | Mammalian Cell | Mouse | His |
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| UGT2A3-5100R | Recombinant Rhesus monkey UGT2A3 Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| UGT2A3-7723Z | Recombinant Zebrafish UGT2A3 | Mammalian Cell | Zebrafish | His |
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| UGT2A3-1879HCL | Recombinant Human UGT2A3 cell lysate | Human | Non |
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| UGT2A3-4913R | Recombinant Rhesus Macaque UGT2A3 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| UGT2A3-4913R-B | Recombinant Rhesus Macaque UGT2A3 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| UGT2A3-9893M | Recombinant Mouse UGT2A3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| UGT2A3-9893M-B | Recombinant Mouse UGT2A3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
UGT2A3 involved in several pathways and played different roles in them. We selected most pathways UGT2A3 participated on our site, such as Pentose and glucuronate interconversions,Ascorbate and aldarate metabolism,Steroid hormone biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UGT2A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Drug metabolism - cytochrome P | AOX2P,MGST1.1,AOX1,FMO4,GSTT1B,GSTM7,GSTT1,GSTA5,UGT1A2,ALDH3A1 |
| Starch and sucrose metabolism | AMY2A4,GYS2,GPIA,GBE1,UGT1A7,SI,TREH,GPI1,UGT1A6A,GAA |
| Chemical carcinogenesis | UGT1A3,GSTO2,CYP2C39,UGT2B15,ADH6,EPHX1,ADH1B,NAT1,CYP3A41A,ADH1 |
| Metabolic pathways | NME6,NMNAT3,PDHA1B,FBP1B,CECR1A,COX8A,PIGYL,MSMO1,UGT8,GGT1 |
| Steroid hormone biosynthesis | HSD3B2,CYP2D9,CYP2D10,HSD17B1,STS,HSD3B6,CYP3A25,PPP1R2,CYP7A1A,CYP2C54 |
| Ascorbate and aldarate metabolism | UGT2A1,UGT1A6A,ALDH3A2,ALDH9A1A.1,UGT5G1,ALDH2.2,ALDH2,UGDH,UGT1A7,ALDH1B1 |
| Pentose and glucuronate interconversions | UGT2B15,UGT1A3,UGT2B7,UGT5G1,UGT1A1,AKR1B8,AKR1B1,AKR1B10,SORD,UGT1A6B |
| Retinol metabolism | SDR16C5A,ADH1,RPE65C,RDH10A,HSD17B6,UGT2B7,DHRS4L2,RDH8,UGT1A6B,CYP2C70 |
| Metabolism of xenobiotics by cytochrome P | GSTM,UGT2B7,UGT1A4,GSTA2,GSTM6,CBR1L,UGT1A2,CBR3,UGT2B15,ADH1 |
Protein Function
UGT2A3 has several biochemical functions, for example, glucuronosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UGT2A3 itself. We selected most functions UGT2A3 had, and list some proteins which have the same functions with UGT2A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| glucuronosyltransferase activity | UGT1A2,UGT5C3,UGT1A1,UGT1B4,UGT1B2,UGT1A9,UGT1A3,EXT1,UGT2B5,UGT5F1 |
Interacting Protein
UGT2A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGT2A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGT2A3.
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References
- Perreault, M; Gauthier-Landry, L; et al. The Human UDP-Glucuronosyltransferase UGT2A1 and UGT2A2 Enzymes Are Highly Active in Bile Acid Glucuronidation. DRUG METABOLISM AND DISPOSITION 41:1616-1620(2013).
- Hardwick, RN; Ferreira, DW; et al. Altered UDP-Glucuronosyltransferase and Sulfotransferase Expression and Function during Progressive Stages of Human Nonalcoholic Fatty Liver Disease. DRUG METABOLISM AND DISPOSITION 41:554-561(2013).
