UGGT1
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Official Full Name
UDP-glucose glycoprotein glucosyltransferase 1 -
Overview
enzyme that catalyzes the addition of a glucose residue from UDP-glucose to an N -linked Man(9)GlcNAc(2)oligosaccharide -
Synonyms
UGGT1;UDP-glucose glycoprotein glucosyltransferase 1;UDP glucose ceramide glucosyltransferase like 1 , UGCGL1;UDP-glucose:glycoprotein glucosyltransferase 1;HUGT1;UDP--Glc:glycoprotein glucosyltransferase;UDP-glucose ceramide glucosyltransferase-lik
Recombinant Proteins
- Mouse
- Zebrafish
- Rat
- Human
- Mammalian Cell
- E.coli
- HEK293
- His
- His&T7
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| UGGT1-17801M | Recombinant Mouse UGGT1 Protein | Mammalian Cell | Mouse | His |
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| UGGT1-4747Z | Recombinant Zebrafish UGGT1 | Mammalian Cell | Zebrafish | His |
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| UGGT1-6431R | Recombinant Rat UGGT1 Protein | Mammalian Cell | Rat | His |
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| UGGT1-1651H | Recombinant Human UGGT1 protein, His & T7-tagged | E.coli | Human | His&T7 | Leu1221~Leu1536 |
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| UGGT1-6032H | Recombinant Human UGGT1 Protein (Leu1221-Leu1536), N-His tagged | E.coli | Human | His | Leu1221-Leu1536 |
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| UGGT1-6087R | Recombinant Rat UGGT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| UGGT1-6087R-B | Recombinant Rat UGGT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| UGGT1-9883M | Recombinant Mouse UGGT1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| UGGT1-9883M-B | Recombinant Mouse UGGT1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
UGGT1 involved in several pathways and played different roles in them. We selected most pathways UGGT1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with UGGT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | UBE2E3,CKAP4,PDIA3,EIF2AK2,DNAJC5GB,SAR1B,HSPA1A,STT3A,DNAJC3A,UBE2D2 |
Protein Function
UGGT1 has several biochemical functions, for example, 1,2-dihydroxy-phenanthrene glycosyltransferase activity,1-phenanthrol glycosyltransferase activity,9-phenanthrol UDP-glucuronosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by UGGT1 itself. We selected most functions UGGT1 had, and list some proteins which have the same functions with UGGT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| acetylgalactosaminyltransferase activity | CHPF2,B3GNTL1,GALNT18A,B4GALNT2,4931440L10Rik,B4GALNT4,CSGALNACT1,GTDC2,B3GALNT2,PIGB |
| mannosyltransferase activity | GLT8D1,B3GNTL1,PIGB,GALNT18A,ZNF408,DPY19L1,POC1BL,POMGNT2,GALNTL4,ALG12 |
| dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity | ALG8,4931440L10Rik,DPY19L1,GLT8D1,GTDC2,PIGB,DPY19L4,GALNT18A,POMGNT2,GALNTL4 |
| chondroitin hydrolase activity | GALNT18A,DPY19L1,B3GNT9-PS,POMGNT2,DPY19L4,B3GNTL1,GLT8D1,B3GNT8,4931440L10Rik,GTDC2 |
| UDP-glucose:glycoprotein glucosyltransferase activity | DPY19L4,GLT8D1,B3GNT8,POC1BL,GALNTL4,GALNT18A,4931440L10Rik,B3GNTL1,B3GNT9-PS,UGGT2 |
| alpha-1,3-mannosyltransferase activity | POMGNT2,DPY19L1,ALG8,ALG2,B3GNT9-PS,PIGB,ALG3,GTDC2,GALNT18A,GALNTL4 |
| alpha-(1->3)-fucosyltransferase activity | GALNT18A,DPY19L4,FUT6,POC1BL,DPY19L1,4931440L10Rik,FUT7,B3GNT9-PS,PIGB,POMGNT2 |
| unfolded protein binding | CDC37,DNAJA3A,MKKS,TCP1,HSPD1,CCT2,NDUFAF1,PFDN1,CLPX,H2-KE2 |
| fucosyltransferase activity | POMGNT2,FUT3,POC1BL,4931440L10Rik,FUT2,FT1,FUT9D,FUT1,GLT8D1,FUT6 |
Interacting Protein
UGGT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UGGT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UGGT1.
Resources
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References
- Takeda, Y; Seko, A; et al. Functional Analysis of Endoplasmic Reticulum Glucosyltransferase (UGGT) Using Synthetic Glycans. TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY 26:107-118(2014).
- Daikoku, S; Seko, A; et al. Glycan structure and site of glycosylation in the ER-resident glycoprotein, uridine 5 '-diphosphate-glucose: glycoprotein glucosyltransferases 1 from rat, porcine, bovine, and human. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 451:356-360(2014).
