UFM1
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Official Full Name
ubiquitin-fold modifier 1 -
Overview
UFM1 is a ubiquitin-like protein that is conjugated to target proteins by E1-like activating enzyme UBA5 (UBE1DC1; MIM;610552) and E2-like conjugating enzyme UFC1 (MIM 610554) in a manner analogous to ubiquitylation (see UBE2M; MIM;603173) (Komatsu et al., 2004 (PubMed 15071506)). -
Synonyms
UFM1;ubiquitin-fold modifier 1;C13orf20, chromosome 13 open reading frame 20;bA131P10.1;BM-002;C13orf20
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rhesus macaque
- Rat
- E.coli
- Mammalian Cell
- HEK293
- GST
- His
- Non
- His&Fc&Avi
Involved Pathway
UFM1 involved in several pathways and played different roles in them. We selected most pathways UFM1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with UFM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
UFM1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by UFM1 itself. We selected most functions UFM1 had, and list some proteins which have the same functions with UFM1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
UFM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UFM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of UFM1.
UBA5;CDK5RAP3;PRKAB1;GSK3B;ARHGDIA;ARHGDIB;DIABLO;RPS6KA6;2_aha_camp;Ufl1
Resources
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References
- Tellermann, A; Witte, T; et al. Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. HIV MEDICINE 16:114-121(2015).
- Liu, H; Gong, M; et al. Mallory-Denk Body (MDB) formation modulates ufmylation expression epigenetically in alcoholic hepatitis (AH) and non-alcoholic steatohepatitis (NASH). EXPERIMENTAL AND MOLECULAR PATHOLOGY 97:477-483(2014).
