Tet3
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Official Full Name
tet methylcytosine dioxygenase 3
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Sf9 Cells
- Mammalian Cells
- Insect Cells
- E.coli
- HEK293
- GST
- His
- Non
- Flag
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TET3-161H | Recombinant Human TET3, GST-tagged | Sf9 Cells | Human | GST | 724-end a.a. |
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| TET3-16654M | Recombinant Mouse TET3 Protein | Mammalian Cells | Mouse | His |
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| TET3-8458Z | Recombinant Zebrafish TET3 | Mammalian Cells | Zebrafish | His |
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| TET3-1762HCL | Recombinant Human TET3 cell lysate | Human | Non |
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| TET3-13H | Recombinant Human TET3 Protein (824-1795), N-6xHis and Flag-tagged | Insect Cells | Human | Flag&His | 824-1795 |
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| TET3-14H | Recombinant Human TET3 Protein (824-1795), N-Flag and C-His tagged | Sf9 Cells | Human | Flag&His | 824-1795 (end) |
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| TET3-301412H | Recombinant Human TET3 protein, GST-tagged | E.coli | Human | GST | Lys316-Leu360 |
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| TET3-9136M | Recombinant Mouse TET3 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| TET3-9136M-B | Recombinant Mouse TET3 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Tet3 involved in several pathways and played different roles in them. We selected most pathways Tet3 participated on our site, such as Epigenetic regulation of gene expression,Gene Expression,TET1,2,3 and TDG demethylate DNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with Tet3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Epigenetic regulation of gene expression | JARID2,SAP30BP,TAF1A,SUDS3,H3F3B.1,DNMT3A,JARID2B,BAZ2A,DNMT3B,PHF19 |
| Gene Expression | EIF4B,ZNF706,ZNF75D,NR6A1,CHST13,ZNF670,SNAPC1,ZKSCAN1,PRMT5,ZFP1 |
| TET1,2,3 and TDG demethylate DNA | TET1,TET2 |
Protein Function
Tet3 has several biochemical functions, for example, DNA binding,metal ion binding,methylcytosine dioxygenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Tet3 itself. We selected most functions Tet3 had, and list some proteins which have the same functions with Tet3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCDC101,ICAM4,HSPA6,FFAR2,VPS11,CDK5RAP3,DMD,PLEKHF1,PRSS21,CAPG |
| metal ion binding | PPM1E,ZBTB2A,ARSB,ZNF76,ISL2B,NCS1A,ITGA2,Itga10&Itgb1,SALL4,TGM1 |
| methylcytosine dioxygenase activity | TET2,ALKBH1,TET1 |
| DNA binding | NR4A2B,EPAS1,LHX6,APITD1,POLR1C,FANCI,RPL7,DDIT3,MYCN,SURF6 |
Interacting Protein
Tet3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Tet3 here. Most of them are supplied by our site. Hope this information will be useful for your research of Tet3.
OGT;a8k1f4_human;SGTA;BAG4;BAG2;STIP1;HCFC1;MLF1;HSF2;PSMD2;HSP90AB1;NUDCD3;q96be0_human;PPP5C;AARSD1;CACYBP;STUB1
Resources
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References
- Bauer, C; Gobel, K; et al. Phosphorylation of TET Proteins Is Regulated via O-GlcNAcylation by the O-Linked N-Acetylglucosamine Transferase (OGT). JOURNAL OF BIOLOGICAL CHEMISTRY 290:4801-4812(2015).
- Inoue, A; Shen, L; et al. Haploinsufficiency, but Not Defective Paternal 5mC Oxidation, Accounts for the Developmental Defects of Maternal Tet3 Knockouts. CELL REPORTS 10:463-470(2015).
