TLR13
-
Official Full Name
toll-like receptor 13 -
Overview
The TLRs form a family of ligand-binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response -
Synonyms
TLR13;toll-like receptor 13;Gm713;AI666735
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| TLR13-16823M | Recombinant Mouse TLR13 Protein | Mammalian Cells | Mouse | His |
|
|
| TLR13-9236M | Recombinant Mouse TLR13 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
|
|
| TLR13-9236M-B | Recombinant Mouse TLR13 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
TLR13 involved in several pathways and played different roles in them. We selected most pathways TLR13 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with TLR13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
TLR13 has several biochemical functions, for example, RNA binding,protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TLR13 itself. We selected most functions TLR13 had, and list some proteins which have the same functions with TLR13. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ANXA10,OTUB2,CP110,SNX1,SKA1,TIMM10,PFN2,SLC26A3,LONRF3,LYSMD1 |
| rRNA binding | RPS9,RPL12,FASTKD2,RPL23A,NOL12,RNASEL,RPS4Y2,RPL9,RPL8,RPF2 |
| RNA binding | RPL29,RPL38,EIF4G2B,SF1,U2AF2A,EXOSC9,ZMAT4,EIF3B,DDX19A,TRNAU1APA |
| protein homodimerization activity | TENM2,RRAGA,SLC14A2,NR6A1A,RBM11,BCL2L2,Il6ra,PRPS1,CER1,GOLGA5 |
Interacting Protein
TLR13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TLR13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TLR13.
Resources
Related Services
Related Products
References
- Wang, Y; Chen, K; et al. Immunizations with hepatitis B viral antigens and a TLR7/8 agonist adjuvant induce antigen-specific immune responses in HBV-transgenic mice. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES 29:31-36(2014).
- Dammermann, W; Bochmann, D; et al. CMV specific cytokine release assay in whole blood is optimized by combining synthetic CMV peptides and toll like receptor agonists. JOURNAL OF IMMUNOLOGICAL METHODS 414:82-90(2014).
