Stxbp2
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Official Full Name
syntaxin binding protein 2 -
Synonyms
STXBP2;syntaxin binding protein 2;ENSMUSG00000004626;Sxtp2;C79054;Sxtbp2;Unc18b;muSec1;Munc18b;Unc18-2;Munc-18b;Munc-18-2;8 A1;8 0.36 cM;syntaxin-binding protein 2;syntaxin-binding protein 2;unc-18B;munc18-2;unc-18 homolog 2;protein unc-18 homolog 2;protein unc-18 homolog B;syntaxin binding protein Munc18-2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| STXBP2-3035H | Recombinant Human STXBP2, His-tagged | E.coli | Human | His | 241-590aa | |
| STXBP2-12479Z | Recombinant Zebrafish STXBP2 | Mammalian Cell | Zebrafish | His |
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| STXBP2-5820R | Recombinant Rat STXBP2 Protein | Mammalian Cell | Rat | His |
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| STXBP2-643HCL | Recombinant Human STXBP2 lysate | HEK293 | Human | Non |
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| STXBP2-5479R | Recombinant Rat STXBP2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| STXBP2-5479R-B | Recombinant Rat STXBP2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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Involved Pathway
Stxbp2 involved in several pathways and played different roles in them. We selected most pathways Stxbp2 participated on our site, such as Insulin Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with Stxbp2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin Signaling | REG1A,RHOJ,MAP3K9,INPP4AA,KIF5B,EHD1,FLOT1,STXBP1A,ARHGAP33,MYO1C |
Protein Function
Stxbp2 has several biochemical functions, for example, protein binding,syntaxin-1 binding,syntaxin-3 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Stxbp2 itself. We selected most functions Stxbp2 had, and list some proteins which have the same functions with Stxbp2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syntaxin-1 binding | RNF40,STXBP3,NSF,VAMP3,SNAP25A,VAMP2,UNC13A,CPLX1,STXBP1,MYO5A |
| protein binding | NPHP4,RXFP1,RPGRIP1,MAGI1,SLC30A1,CSDE1,MAD1L1,CHID1,ARHGEF38,RUVBL2 |
Interacting Protein
Stxbp2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Stxbp2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Stxbp2.
pi3p;15-deoxy-delta(12,14;BAG2;SMS;Tubg1;PDK1;Smad3;FANCI
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References
- Esmaeilzadeh, H; Bemanian, MH; et al. Novel Patient with Late-Onset Familial Hemophagocytic Lymphohistiocytosis with STXBP2 Mutations Presenting with Autoimmune Hepatitis, Neurological Manifestations and Infections Associated with Hypogammaglobulinemia. JOURNAL OF CLINICAL IMMUNOLOGY 35:22-25(2015).
- Kaufman, KM; Linghu, B; et al. Whole-Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis. ARTHRITIS & RHEUMATOLOGY 66:3486-3495(2014).
