SYTL3
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Official Full Name
synaptotagmin-like 3 -
Overview
The protein encoded by this gene belongs to the family of synaptotagmin-like proteins (SLPs). SLPs are peripheral membrane proteins that interact with RAB27A protein, and play a role in vesicular trafficking. Unlike, SLPs 1 and 2, this protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
SYTL3;synaptotagmin-like 3;synaptotagmin-like protein 3;exophilin 6;SLP3;Exophilin-6;MGC105130;MGC118883;MGC118884;MGC118885;synaptotagmin like 3;SYTL3_HUMAN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SYTL3-3090H | Recombinant Human SYTL3, His-tagged | E.coli | Human | His | 302-610aa | |
| SYTL3-1298HCL | Recombinant Human SYTL3 293 Cell Lysate | HEK293 | Human | Non |
|
Involved Pathway
SYTL3 involved in several pathways and played different roles in them. We selected most pathways SYTL3 participated on our site, such as Deregulation of Rab and Rab Effector Genes in Bladder Cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYTL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Deregulation of Rab and Rab Effector Genes in Bladder Cancer | SYTL1,RPH3A,MLPH,EXPH5,RPH3AL,GCC2,SYTL4,UNC13D,TBC1D10A,SYTL2 |
Protein Function
SYTL3 has several biochemical functions, for example, Rab GTPase binding,calcium ion binding,calcium-dependent phospholipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYTL3 itself. We selected most functions SYTL3 had, and list some proteins which have the same functions with SYTL3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Rab GTPase binding | ULK1,DENND5A,LLGL2,CHML,NDRG1,SLC6A4,NGFR,RAB11FIP5,RABGAP1L,STX4A |
| neurexin family protein binding | NLGN3B,LRRTM2,SYTL1,NLGN2A,NLGN3A,SYTL4,SYTL2,NLGN4Y,NLGN3,CASK |
| syntaxin binding | SYT7,CAV1,SYT7B,SYT5,RPH3AL,VPS11,STX8,CPLX3B,SYTL2,SYT5B |
| calcium ion binding | CDH20,SLC25A24,SYT16,ANXA1,TLL2,S100G,LTBP4,CRNN,EFHD1,EFEMP2 |
| calcium-dependent phospholipid binding | ANXA4,PCLO,ANXA9,TC2N,ANXA5B,CCDC167,SYT12,SYT17,SYT2,SYTL4 |
| clathrin binding | SYT1,HIP1RB,SYT5B,LRRK2,SYT1B,LDLRAP1,SYTL4,SYT15,SYT4,SYT17 |
Interacting Protein
SYTL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYTL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYTL3.
Dlg4;barA
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