SYT4
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Official Full Name
synaptotagmin IV -
Overview
Synaptotagmin-4 is a protein that in humans is encoded by the SYT4 gene. -
Synonyms
SYT4;synaptotagmin IV;synaptotagmin-4;HsT1192;KIAA1342;Synaptotagmin4;SynaptotagminIV;SYT 4;Syt IV;SytIV;synaptotagmin 4;OTTHUMP00000163444
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Rat
- Mus musculus
- E.coli
- Mammalian Cell
- HEK293
- E.coli expression system
- HEK293T
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
SYT4 involved in several pathways and played different roles in them. We selected most pathways SYT4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SYT4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SYT4 has several biochemical functions, for example, calcium ion binding,NOT calcium-dependent phospholipid binding,clathrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYT4 itself. We selected most functions SYT4 had, and list some proteins which have the same functions with SYT4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SH3YL1,CXorf48,PPP6R3,IL4,SULT2B1,BTN3A1,SIN3B,NR2E3,FATE1,KLK15 |
| phosphatidylserine binding | OSBPL8,TRIM72,RASGRP1,GAS6,SCIN,OSBPL5,RS1,AP1S2,CD300A,ANXA9 |
| syntaxin binding | DOC2B,STXBP5L,TMED10,SYT5,SCFD1,CPLX3B,CPLX4,GOLGA2,SEC22B,SYT15 |
| clathrin binding | CCDC167,SYT17,SYT5B,DNER,SYT10,SYT9B,SYT1A,SYT9,SYT11A,SMAP1 |
| NOT calcium-dependent phospholipid binding | SYT11B,SYT14,SYT6,SYT16,MCTP1,MCTP2,SYT13 |
| calcium ion binding | ASPN,CDH10,DLC,JAG1A,MMP13A,TBC1D9B,PLCH2,FAT3A,PCDH1G2,SYTL4 |
Interacting Protein
SYT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYT4.
SGTA;NBR1
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References
- Mori, Y; Fukuda, M; et al. Synaptotagmin IV Acts as a Multi-Functional Regulator of Ca2+-Dependent Exocytosis. NEUROCHEMICAL RESEARCH 36:1222-1227(2011).
- Kanno, E; Fukuda, M; et al. Increased plasma membrane localization of O-glycosylation-deficient mutant of synaptotagmin h in PC12 cells. JOURNAL OF NEUROSCIENCE RESEARCH 86:1036-1043(2008).
