SYNM
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Official Full Name
synemin, intermediate filament protein -
Overview
The protein encoded by this gene is an intermediate filament (IF) family member. IF proteins are cytoskeletal proteins;that confer resistance to mechanical stress and are encoded by a dispersed multigene family. This protein has been;found to form a linkage between desmin, which is a subunit of the IF network, and the extracellular matrix, and;provides an important structural support in muscle. Two alternatively spliced variants encoding different isoforms;have been described for this gene. -
Synonyms
SYNM;synemin, intermediate filament protein;desmuslin , DMN;synemin;KIAA0353;SYN;synemin alpha;synemin beta;Desmuslin;DMN
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SYNM-16315M | Recombinant Mouse SYNM Protein | Mammalian Cell | Mouse | His |
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| SYNM-6372C | Recombinant Chicken SYNM | Mammalian Cell | Chicken | His |
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| SYNM-8916M | Recombinant Mouse SYNM Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SYNM-8916M-B | Recombinant Mouse SYNM Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SYNM involved in several pathways and played different roles in them. We selected most pathways SYNM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SYNM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
SYNM has several biochemical functions, for example, intermediate filament binding,protein binding,protein binding, bridging. Some of the functions are cooperated with other proteins, some of the functions could acted by SYNM itself. We selected most functions SYNM had, and list some proteins which have the same functions with SYNM. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of muscle | OBSCN,MYL6B,ASPH,CAPN3,SMTN,TPM4,MYBPC3,MYLPF,MYH11,MYBPH |
| intermediate filament binding | NME2,PKP2,MTM1,EVPL,NES,PKP1,EVPLA |
| vinculin binding | ACTN1,NRAP,TLN1,PXN,DAG1,SORBS3,DMD,CTNNA1,C22orf28 |
| structural constituent of cytoskeleton | TUBA1B,TUBA8L3,KRT2,KRT5,TUBA3E,TUBA1L,TUBB4A,DES,ARPC4,TUBB |
| protein binding | BICC1,DHX38,AGT,TPX2,C6orf108,BIRC5,PFKL,FRMD8,RFWD3,TAPBP |
| protein binding, bridging | FGA,PSMC6,FSCN2,SPRR1A,DDX20,BFAR,SLC9A1,NUFIP1,PPP4R2,CNKSR1 |
| structural molecule activity | IVL,NPHP1,KRT72-PS,CLTCA,KRT76,KRT9,LAMA5,MAP7D1,PRR9,KRT83 |
Interacting Protein
SYNM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYNM here. Most of them are supplied by our site. Hope this information will be useful for your research of SYNM.
Ttn;Hmga2
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References
- Luna, G; Lewis, GP; et al. Expression profiles of nestin and synemin in reactive astrocytes and Muller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin. MOLECULAR VISION 16:2511-2523(2010).
- Izmiryan, A; Peltekian, E; et al. Synemin Isoforms in Astroglial and Neuronal Cells from Human Central Nervous System. NEUROCHEMICAL RESEARCH 35:881-887(2010).
