SV2A
-
Official Full Name
synaptic vesicle glycoprotein 2A -
Overview
Synaptic vesicle glycoprotein 2A is a ubiquitous synaptic vesicle protein that in humans is encoded by the SV2A gene.The protein is targeted by the anti-epileptic drug (AED) levetiracetam. -
Synonyms
SV2A;synaptic vesicle glycoprotein 2A;KIAA0736;SV2;OTTHUMP00000014065;Synaptic vesicle glycoprotein 2;Synaptic vesicle protein 2a;OTTHUMP00000014066
Recombinant Proteins
- Mouse
- Rat
- Cynomolgus
- Human
- Bovine
- Mammalian Cell
- HEK293
- Wheat Germ (in vitro)
- E. coli
- Yeast
- E.coli
- His
- Non
- GST
- His&Myc
- N-His&C-Myc
- His&Fc&Avi
Involved Pathway
SV2A involved in several pathways and played different roles in them. We selected most pathways SV2A participated on our site, such as ECM-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SV2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ECM-receptor interaction | COL3A1,THBS4B,THBS4,COL11A1A,COL6A3,LAMB1,ITGA4,COL4A1,ITGA2,CD47 |
Protein Function
SV2A has several biochemical functions, for example, protein kinase binding,receptor activity,transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SV2A itself. We selected most functions SV2A had, and list some proteins which have the same functions with SV2A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transmembrane transporter activity | ATP5F1,CX43,SV2BA,SLC22A23,ATP5B,SLC22A7B.1,SLC17A9B,SLC22A20,ATP5L,ATP5D |
| receptor activity | RRBP1B,PAQR4,CD86,GUCY1B3,PVR,DERL1,MED17,ADIPOR1,NEO1,TNFRSF25 |
| protein kinase binding | DNM1,BORA,AKAP7,SMAD1,EEF2,MLKL,MAPKAP1,Fert2,PRKCZ,RAD9 |
Interacting Protein
SV2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SV2A here. Most of them are supplied by our site. Hope this information will be useful for your research of SV2A.
ETS1;ATXN1;P
Resources
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References
- Strotmeier, J; Mahrhold, S; et al. Identification of the synaptic vesicle glycoprotein 2 receptor binding site in botulinum neurotoxin A. FEBS LETTERS 588:1087-1093(2014).
- Sgro, AE; Bajjalieh, SM; et al. Single-Axonal Organelle Analysis Method Reveals New Protein-Motor Associations. ACS CHEMICAL NEUROSCIENCE 4:277-284(2013).
