SUN1
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Official Full Name
Sad1 and UNC84 domain containing 1 -
Overview
This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described. -
Synonyms
UNC84A;FLJ12407;KIAA0810;MGC176649;SUN domain-containing protein 1;unc-84 homolog A;OTTHUMP00000199968;OTTHUMP00000199969;OTTHUMP00000199971;OTTHUMP00000199972;OTTHUMP00000199973;OTTHUMP00000199974;OTTHUMP00000199975;protein unc-84 homolog A;sad1/unc-84 protein-like 1;Sad1 unc-84 domain protein 1;SUN1;Sad1 and UNC84 domain containing 1
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| SUN1-16240M | Recombinant Mouse SUN1 Protein | Mammalian Cell | Mouse | His |
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| SUN1-2649Z | Recombinant Zebrafish SUN1 | Mammalian Cell | Zebrafish | His |
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| SUN1-1888HCL | Recombinant Human SUN1 cell lysate | Human | Non |
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| SUN1-8873M | Recombinant Mouse SUN1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| SUN1-8873M-B | Recombinant Mouse SUN1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
SUN1 involved in several pathways and played different roles in them. We selected most pathways SUN1 participated on our site, such as Cell Cycle,Meiosis,Meiotic synapsis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SUN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Meiosis | ACD,STAG2,MND1,POT1,PSMC3IP,TERF1,DIDO1,FKBP6,TEX12,STAG1 |
| Cell cycle | CTDNEP1,NDEL1B,PKMYT1,MPEG1.1,HAUS2,TUBGCP5,HDAC1,DIDO1,CDC6,BUB1 |
| Meiotic synapsis | SYNE2,FKBP6,SYNE1,STAG1,TEX12,STAG2,TERF2,POT1,ACD,SYCE1 |
Protein Function
SUN1 has several biochemical functions, for example, lamin binding,protein anchor,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SUN1 itself. We selected most functions SUN1 had, and list some proteins which have the same functions with SUN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | CCND3,MAPK14,RAB25,BLOC1S5,LOXL4,PROC,ECT2,THOC2,CACNG1,SLC4A1AP |
| protein anchor | PDCD6,NUP153,MYH9,SLC4A1,CIB1,SUN3,SUN5,AKAP6,RAPSN,ALG14 |
| lamin binding | SYNE1,NARF,LBR,TMEM201,IFI27,TOR1AIP1,PPP4C,PLCB1,BNIP3L,SUN2 |
Interacting Protein
SUN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SUN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SUN1.
SYNE1;SYNE2;env;pilQ;SYNE1;SYNE2
Resources
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References
- Randles, KN; Lam, L; et al. Nesprins, But Not Sun Proteins, Switch Isoforms at the Nuclear Envelope During Muscle Development. DEVELOPMENTAL DYNAMICS 239:998-1009(2010).
- Hodzic, DM; Yeater, DB; et al. Sun2 is a novel mammalian inner nuclear membrane protein. JOURNAL OF BIOLOGICAL CHEMISTRY 279:25805-25812(2004).
- Fujimuro, M; Tanaka, K; et al. Son1p is a component of the 26S proteasome of the yeast Saccharomyces cerevisiae. FEBS LETTERS 423:149-154(1998).
- Varas, J; Graumann, K; et al. Absence of SUN1 and SUN2 proteins in Arabidopsis thaliana leads to a delay in meiotic progression and defects in synapsis and recombination. PLANT JOURNAL 81:329-346(2015).
