STXBP3
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Official Full Name
syntaxin binding protein 3 -
Overview
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. -
Synonyms
STXBP3;syntaxin binding protein 3;syntaxin-binding protein 3;UNC 18C;Munc18 3;Munc18 c;Platelet Sec1 protein;Protein unc-18 homolog 3;Protein unc-18 homolog C;PSP;STXB3_HUMAN;STXBP 3;Sxtbp3;syntaxin 4 binding protein;Unc 18 3;Unc 18 homolog 3;Unc-18C;Unc18-3;MUNC18C;MUNC18-3
Recombinant Proteins
- Human
- Zebrafish
- Chicken
- Mouse
- E.coli
- Insect Cells
- Mammalian Cell
- Insect Cell
- E. coli
- HEK293
- HEK293T
- His
- His&GST
- Non
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| STXBP3-3036H | Recombinant Human STXBP3, His-tagged | E.coli | Human | His | 242-592aa | |
| STXBP3-3786H | Recombinant Human STXBP3 protein, His&GST-tagged | Insect Cells | Human | His&GST | Met1-Glu592 | |
| STXBP3-12639Z | Recombinant Zebrafish STXBP3 | Mammalian Cell | Zebrafish | His |
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| STXBP3-3567C | Recombinant Chicken STXBP3 | Mammalian Cell | Chicken | His |
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| STXBP3-600HCL | Recombinant Human STXBP3 cell lysate | Insect Cell | Human | Non |
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| STXBP3-001H | Recombinant Human syntaxin binding protein 3 Protein, His-tagged | E. coli | Human | His | 84-231aa |
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| STXBP3-2986H | Recombinant Human STXBP3 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| STXBP3-3037H | Recombinant Human STXBP3 protein, GST-tagged | E. coli | Human | GST | 242-592 aa |
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| STXBP3-5935H | Recombinant Human STXBP3 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Stxbp3-6210M | Recombinant Mouse Stxbp3 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
STXBP3 involved in several pathways and played different roles in them. We selected most pathways STXBP3 participated on our site, such as Disinhibition of SNARE formation,Hemostasis,Insulin Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with STXBP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Hemostasis | NADL1.1,KIF22,GAS6,PIK3R6,ANXA2B,IRF1B,MMRN1,PROCA,GATA2,F9B |
| Translocation of GLUT4 to the plasma membrane | RALAA,MYO1C,RAB10,RALAB |
| Disinhibition of SNARE formation | STXBP3A |
| Platelet activation, signaling and aggregation | G6b,FCER1GL,CD9A,SPARC,HRG,ABHD12,MMRN2A,STXBP3A,CAP1,WDR1 |
| Insulin Signaling | REG1A,MAP3K2,INPP4AA,GRB14,RRAD,KIF5B,MAP4K5,STXBP3A,MAP3K9,CAP1 |
| Vesicle-mediated transport | PPP6C,SH3D19,CX30.3,RALAB,GAK,SNX9A,GJB3,AP4B1,HIP1RB,GJA4 |
| Membrane Trafficking | SEC22A,TRAPPC2,SNF8,AP1S3A,FTH1A,BLOC1S3,COPE,TRAPPC4,CNO,PPP6C |
| Response to elevated platelet cytosolic Ca2+ | STXBP3A,F13A1A.1,SPARC,CLU,HRG,CAP1,SRGN,SERPINF2B,MMRN1,TFA |
Protein Function
STXBP3 has several biochemical functions, for example, protein binding,syntaxin binding,syntaxin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STXBP3 itself. We selected most functions STXBP3 had, and list some proteins which have the same functions with STXBP3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| syntaxin-1 binding | SNAP25B,SNAP25,SNPH,VAMP2,DAPK1,CCDC167,VAMP3,STXBP1,CPLX1,SNAP25A |
| protein binding | ATXN7L1,SH3GL3,KIF20A,KCNG3,ADA,CARHSP1,GGACT,SYNDIG1,BIN2,DHX32 |
| syntaxin binding | NAPG,VPS52,NAPAA,ABL1,SYT9B,RPH3A,SYT7B,CPLX4,SYT4,SYT16 |
Interacting Protein
STXBP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STXBP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of STXBP3.
RPL3;katG;pi3p;FN1
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References
- Rodriguez, AR; Muller, LPD; et al. The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. JOURNAL OF COMPARATIVE NEUROLOGY 522:1411-1443(2014).
- Zhang, Y; Kang, YH; et al. Cab45b, a Munc18b-interacting Partner, Regulates Exocytosis in Pancreatic beta-Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 284:20840-20847(2009).
