STX4
-
Official Full Name
syntaxin 4 -
Overview
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones. -
Synonyms
STX4;syntaxin 4;STX4A, syntaxin 4A (placental);syntaxin-4;p35 2;NY REN 31 antigen;Renal carcinoma antigen NY REN 31;Renal carcinoma antigen NY-REN-31;STX4_HUMAN;STX4A;Syntaxin 4A;syntaxin 4A (placental);p35-2
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Mus musculus
- E.coli
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli expression system
- Mammalian cells
- HEK293T
- His
- GST
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
STX4 involved in several pathways and played different roles in them. We selected most pathways STX4 participated on our site, such as SNARE interactions in vesicular transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| SNARE interactions in vesicular transport | STX2,VTI1B,SEC22B,USE1,VAMP8,STX3A,VTI1A,VAMP5,STX5AL,SNAP23.2 |
Protein Function
STX4 has several biochemical functions, for example, SNAP receptor activity,SNARE binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX4 itself. We selected most functions STX4 had, and list some proteins which have the same functions with STX4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SNARE binding | VAMP7,TNFAIP2,GOSR1,GABARAPL2,SEC22C,STX11B.2,VAMP8,YKT6,VTI1A,MYO5A |
| protein binding | RGS19,TECPR2,CTGF,HOXB5,AZI2,NADK,RTN4R,COPS8,BIN1,GDI1 |
| sphingomyelin phosphodiesterase activator activity | STX4A |
| SNAP receptor activity | STX16,STX12,STX11A,STX18,VTI1B,STX4A,STX6,STX11B.1,STX3,STX1B |
Interacting Protein
STX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX4.
VAMP3;STX7;STX6;VAMP4;CYBRD1
Resources
Related Services
Related Products
References
