STIM2
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Official Full Name
stromal interaction molecule 2 -
Overview
Ca2+ is a key second messenger in many intracellular signaling pathways. Ca2+ signals control many cellular functions ranging from short-term responses such as contraction and secretion to longer-term regulation of cell growth and proliferation. Stromal i -
Synonyms
STIM2;stromal interaction molecule 2;FLJ39527;KIAA1482
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| STIM2-3005H | Recombinant Human STIM2, GST-tagged | E.coli | Human | GST | 446-595aa | |
| STIM2-005H | Recombinant Human STIM2 Protein, His-tagged | E.coli | Human | His | 525-674 aa | |
| RFL3056MF | Recombinant Full Length Mouse Stromal Interaction Molecule 2(Stim2) Protein, His-Tagged | E.coli expression system | Mus musculus | His | Full L. Full Length of Mature Protein (15-746) |
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| STIM2-2885H | Recombinant Human STIM2 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| STIM2-4194H | Recombinant Human STIM2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Stim2-582M | Recombinant Mouse Stim2 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
STIM2 involved in several pathways and played different roles in them. We selected most pathways STIM2 participated on our site, such as Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Calcium signaling pathway | NOS3,P2RX5,PHKG1B,AGTR1,HTR4,PPP3R2,HTR5A,MYLK,ERBB3B,CHRNA7 |
Protein Function
STIM2 has several biochemical functions, for example, calcium channel regulator activity,calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIM2 itself. We selected most functions STIM2 had, and list some proteins which have the same functions with STIM2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| store-operated calcium channel activity | TRPC4,TRPC2,TRPC7,ORAI2,TRPC2B,TRPC5,TRPC6A,ORAI1B,ORAI1,TRPC5A |
| calcium ion binding | PCDH10B,CALB2A,SLIT2,PVALB6,RASGRP1,PCDHB6,PCDHGA5,CALB2,RHOT2,DLL4 |
| calcium channel regulator activity | STIM1B,NRXN3,SRI,TSPAN13A,SGK2,Crisp4,HPCAL4,CACNA2D3,TSPAN13,NRXN2 |
| protein binding | C10orf137,AMPH,ATG3,MUSK,TGFA,NFE2L3,ARHGAP33,BLOC1S1,TICAM2,EXOC1 |
Interacting Protein
STIM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIM2.
CALM;PRKAB2;PRKAA2;STIM1;PRPF40A
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References
- Matsumoto, M; Baba, Y; et al. Role of STIM-dependent Ca2+ Influx in Regulatory B Cells. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 133:419-425(2013).
- Matsumoto, M; Fujii, Y; et al. The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production. IMMUNITY 34:703-714(2011).
- Thiel, M; Wolfs, MJ; et al. Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry. IMMUNOLOGY 129:28-40(2010).
- Skibinska-Kijek, A; Wisniewska, MB; et al. Immunolocalization of STIM1 in the mouse brain. ACTA NEUROBIOLOGIAE EXPERIMENTALIS 69:413-428(2009).
