STAG1
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Official Full Name
stromal antigen 1 -
Overview
This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. -
Synonyms
STAG1;stromal antigen 1;cohesin subunit SA-1;SA 1;SCC3A;SCC3 homolog 1;nuclear protein stromal antigen 1;SA1;DKFZp781D1416
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| STAG1-2986H | Recombinant Human STAG1, GST-tagged | E.coli | Human | GST | 880-1221aa | |
| STAG1-16089M | Recombinant Mouse STAG1 Protein | Mammalian Cells | Mouse | His |
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| STAG1-29260TH | Recombinant Human STAG1, His-tagged | E.coli | Human | His | 872-1258 a.a. |
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| STAG1-1430HCL | Recombinant Human STAG1 293 Cell Lysate | HEK293 | Human | Non |
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| STAG1-8771M | Recombinant Mouse STAG1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| STAG1-8771M-B | Recombinant Mouse STAG1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
STAG1 involved in several pathways and played different roles in them. We selected most pathways STAG1 participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Cohesin Loading onto Chromatin, which may be useful for your reference. Also, other proteins which involved in the same pathway with STAG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell cycle | KIF18A,CETN2,GADD45AA,CDC14AB,MAPRE1A,CENPC1,RAD9B,CEP135,CENPW,RBBP4 |
| M Phase | NIPBLA,CENPL,CCDC99,ITGB3BP,NCAPD3,AHCTF1,ANKLE2,INCENP,GOLGA2,MAU2 |
| Cell Cycle, Mitotic | GORASP2,B9D2,CEP76,HIST4H4,CLASP1A,VRK1,DYNC1I2,LMNB1,GORASP1,E2F3 |
| Establishment of Sister Chromatid Cohesion | WAPAL,PDS5B,PDS5A,ESCO2,STAG2,ESCO1,CDCA5 |
| Meiotic synapsis | SYCP1,POT1,TINF2,SYNE2,TEX12,STAG2,DIDO1,ACD,POT1A,SYNE1 |
| Meiosis | TERF1,MSH5,PSMC3IP,SPO11,SUN1,SYCP2,TERF2,TINF2,POT1,FKBP6 |
| Cohesin Loading onto Chromatin | MAU2,NIPBLB,NIPBL,WAPAL,NIPBLA,STAG2,PDS5B,PDS5A |
Protein Function
STAG1 has several biochemical functions, for example, chromatin binding,protein binding,transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STAG1 itself. We selected most functions STAG1 had, and list some proteins which have the same functions with STAG1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | IKZF3,ALX4,FOXF2,IRF2,GATA2B,BARX1,CSRNP3,CEBPA,MSX1,ATF1 |
| protein binding | LGALS6,ABCF1,ZNF404,TRPV4,GABBR2,TRPM6,SMR3B,DDX20,ARL4D,CAMSAP1L1 |
| chromatin binding | NCAPD3,SATB1,GM606,RING1,UBTFL,APBB1,CITED1,HMGB1,ZFP143,NONO |
Interacting Protein
STAG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STAG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of STAG1.
SMC3;RAD21;WAPAL
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