ST6GALNAC5
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Official Full Name
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 -
Overview
ST6GALNAC5 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter;cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 (PubMed 12668675)). -
Synonyms
ST6GALNAC5;ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;sialyltransferase 7 ((alpha N acetylneuraminyl 2,3 beta galactosyl 1,3) N acetyl galactosaminide alpha 2,6 sialyltransferase) E , SIAT7E;alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;MGC3184;ST6GalNAcV;Alpha N acetylgalactosaminide alpha 2,6 sialyltransferase 5;GalNAc alpha 2,6 sialyltransferase V;GD1 alpha synthase;Sialyltransferase 7E;SIAT7E;ST6GalNAc V;SIAT7-E;GalNAc alpha-2,6-sialyltransferase V;alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase V;ST6 neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5;alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase E;sialyltransferase 7 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E;sialyltransferase 7 ((alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ST6GALNAC5-4887C | Recombinant Chicken ST6GALNAC5 | Mammalian Cell | Chicken | His |
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| ST6GALNAC5-1435HCL | Recombinant Human ST6GALNAC5 293 Cell Lysate | HEK293 | Human | Non |
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Involved Pathway
ST6GALNAC5 involved in several pathways and played different roles in them. We selected most pathways ST6GALNAC5 participated on our site, such as Glycosphingolipid biosynthesis - ganglio series,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST6GALNAC5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | GPAT2,ACACB,URAD,Ckmm,SPR,AGPAT9L,PYGL,PGM3,H6PD,CECR1 |
| Glycosphingolipid biosynthesis - ganglio series | HEXA,GLB1,SLC33A1,ST6GALNAC4,ST8SIA5,ST6GALNAC6,B4GALNT1,ST3GAL1,ST3GAL2,HEXB |
Protein Function
ST6GALNAC5 has several biochemical functions, for example, alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity,sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST6GALNAC5 itself. We selected most functions ST6GALNAC5 had, and list some proteins which have the same functions with ST6GALNAC5. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity | ST6GALNAC1.2,ST6GALNAC1,ST6GALNAC6,ST6GALNAC3,ST6GALNAC5B,ST6GALNAC4 |
| sialyltransferase activity | ST6GAL2A,ST3GAL3B,ST6GALNAC6,ST3GAL5,ST6GAL1,ST3GAL3A,ST8SIA3,ST6GALNAC3,ST6GALNAC1.2,ST6GALNAC5B |
Interacting Protein
ST6GALNAC5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST6GALNAC5 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST6GALNAC5.
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References
- Kroes, RA; He, HA; et al. Overexpression of ST6GalNAcV, a ganglioside-specific alpha 2,6-sialyltransferase, inhibits glioma growth in vivo. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107:12646-12651(2010).
