ST6GAL2
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Official Full Name
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 -
Overview
Sialyltransferases, such as ST6GAL2 (EC 2.4.99.1), are type II transmembrane proteins that catalyze the transfer of sialic acid from CMP-sialic acid to an acceptor carbohydrate, usually to the terminal ends of carbohydrate chains. -
Synonyms
ST6GAL2;ST6 beta-galactosamide alpha-2,6-sialyltranferase 2;sialyltransferase 2 (monosialoganglioside sialyltransferase) , SIAT2;beta-galactoside alpha-2,6-sialyltransferase 2;KIAA1877;St6GalII;6-sialyltransferase 2;6-ST 2;Alpha 2;Alpha 2,6 ST 2;beta galactoside alpha 2,6 sialyltransferase II;Beta-galactoside alpha-2;CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase;CMP-N-acetylneuraminate-beta-galactosamide-alpha-2;EC 2.4.99.1;FLJ30711;FLJ37730;FLJ38334;hST6Gal II;Sialyltransferase 2;SIAT2;SIAT2_HUMAN;ST6 beta galactosamide alpha 2,6 sialyltranferase 2;ST6Gal II;alpha 2,6-ST 2;beta-galactoside alpha-2,6-sialyltransferase II;sialyltransferase 2 (monosialoganglioside sialyltransferase);CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,6-sialyltransferase 2
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| ST6GAL2-4026C | Recombinant Chicken ST6GAL2 | Mammalian Cell | Chicken | His |
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| ST6GAL2-1703HCL | Recombinant Human ST6GAL2 cell lysate | Human | Non |
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| RFL16738BF | Recombinant Full Length Bovine Beta-Galactoside Alpha-2,6-Sialyltransferase 2(St6Gal2) Protein, His-Tagged | E.coli expression system | Bovine | His | Full L. Full Length (1-495) |
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Involved Pathway
ST6GAL2 involved in several pathways and played different roles in them. We selected most pathways ST6GAL2 participated on our site, such as N-Glycan biosynthesis,Other types of O-glycan biosynthesis,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST6GAL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other types of O-glycan biosynthesis | GXYLT1B,ST6GAL1,B4GALT2,POMT1,B3GALTL,COLGALT2,OGT.1,GXYLT2,POGLUT1,OGT |
| N-Glycan biosynthesis | MGAT3A,B4GALT3,B4GALT2,MAN1C1,TUSC3,ALG2,STT3B,DPM1,RABGNT1,DOLK |
| Metabolic pathways | CDIPT,GALC,TCIRG1,NOS2A,B3GNT6,SQLEA,UGT1AB,AK7,DHRS4,PIGP |
Protein Function
ST6GAL2 has several biochemical functions, for example, beta-galactoside alpha-2,6-sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST6GAL2 itself. We selected most functions ST6GAL2 had, and list some proteins which have the same functions with ST6GAL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-galactoside alpha-2,6-sialyltransferase activity | ST6GAL2A,ST6GAL1,ST6GAL2B |
Interacting Protein
ST6GAL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST6GAL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST6GAL2.
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References
- Chen, YC; Huang, RL; et al. Methylomics analysis identifies epigenetically silenced genes and implies an activation of beta-catenin signaling in cervical cancer. INTERNATIONAL JOURNAL OF CANCER 135:117-127(2014).
- Ma, HY; Cheng, L; et al. Reversal Effect of ST6GAL 1 on Multidrug Resistance in Human Leukemia by Regulating the PI3K/Akt Pathway and the Expression of P-gp and MRP1. PLOS ONE 9:-(2014).
