ST3GAL2
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Official Full Name
ST3 beta-galactoside alpha-2,3-sialyltransferase 2 -
Overview
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. -
Synonyms
ST3GAL2;ST3 beta-galactoside alpha-2,3-sialyltransferase 2;sialyltransferase 4B (beta galactosidase alpha 2,3 sialytransferase) , SIAT4B;CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2;ST3GalA.2;ST3GALII;SIAT4-B;ST3Gal II
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Rhesus macaque
- Chicken
- CHO
- HEK293
- Mammalian Cell
- His
- Non
- His&Fc&Avi
Involved Pathway
ST3GAL2 involved in several pathways and played different roles in them. We selected most pathways ST3GAL2 participated on our site, such as Mucin type O-Glycan biosynthesis,Glycosaminoglycan biosynthesis - keratan sulfate,Glycosphingolipid biosynthesis - globo series, which may be useful for your reference. Also, other proteins which involved in the same pathway with ST3GAL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glycosaminoglycan biosynthesis - keratan sulfate | B3GNT2,B3GNT1,CHST6,CHST1,CHST2,B4GALT2,B3GNT7,B4GALT4,CHST4,ST3GAL3B |
| Glycosphingolipid biosynthesis - ganglio series | ST6GALNAC3,ST6GALNAC4,ST3GAL1,B4GALNT1,ST8SIA1,HEXB,ST6GALNAC5,GLB1,B3GALT4,ST3GAL5 |
| Mucin type O-Glycan biosynthesis | GALNT13,GALNTL6,GALNT4,GALNTL5,GALNT10,GALNT14,B3GNT6,GALNT12,GCNT1,ST3GAL1 |
| Glycosphingolipid biosynthesis - globo series | B3GALT5,GLA,A4GALT,GBGT1,HEXB,ST3GAL1,FUT9A,B3GALNT1,ST8SIA1,FUT2 |
| Metabolic pathways | SDHDB,GLUD2,PLB1,ATP6V0A2B,SPTLC3,ATP6V0B,AK2,ALDOA,MGAT1B,CHPF |
Protein Function
ST3GAL2 has several biochemical functions, for example, beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ST3GAL2 itself. We selected most functions ST3GAL2 had, and list some proteins which have the same functions with ST3GAL2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | ST3GAL4,ST3GAL3,ST3GAL1,ST3GAL2L,ST3GAL5,ST3GAL3A,ST3GAL3B,ST3GAL5L |
Interacting Protein
ST3GAL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ST3GAL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ST3GAL2.
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References
- Gomes, J; Magalhaes, A; et al. Glycophenotypic Alterations Induced by Pteridium aquilinum in Mice Gastric Mucosa: Synergistic Effect with Helicobacter pylori Infection. PLOS ONE 7:-(2012).
